| Chapter 1. The current status of enzyme and small-molecule catalyzed kinetic resolution of racemic tertiary alcohols will be discussed. Applications of kinetic resolution of racemic tertiary alcohols as a means towards target-oriented synthesis will also be presented.;Chapter 2. Synthesis of the novel amino acid Boc-(2 S, 3S)-beta-(Me)-pi-(Me)-His-OH will be presented. The incorporation of this amino acid into a pentameric peptide catalyst will also be discussed. Advances employing this catalyst for the kinetic resolution of racemic tertiary alcohols will then be detailed. |
