Synthesis And Performance Of New Coordination Compounds Based On Fluorescent Components

Coordination compounds are one kind of organic-inorganic hybrid materials which are formed by self-assembly of organic ligands and metal units through coordination bonds.A variety of applications including gas adsorption and separation,drug slow release,chemical sensing,optical materials,heterogeneous catalysis and other fields have been revealed.Because of the abundant light-emitting sites,wide light-emitting wavelength range,adjustable pore size and structure,and easy multi-functional modification of the coordination compound,so they have broad application prospects in the fields of illumination,display,imaging,fluorescence detection and other fields.Therefore,in this thesis,through the adoption of fluorescent ligands and fluorescent guest molecules,a series of new complexes have been synthesized,and their applications in fluorescence sensing,controlled drug release and fluorescence regulation have been studied.The main research results of this thesis are as follows:1.Synthesis and sensing research of novel complex based on fluorescent ligand.Firstly,by using the fluorescent ligand o-phenanthroline,three carboxylic acid ligands and Zn²⁺,three new complexes(HNU-40?42)with different dimensions have been synthesized.The three complexes showed good selectivity,anti-interference and recyclability for the detection of nitrobenzene molecules.Secondly,a new type of complex was synthesized using fluorescence with 5-chloro-8-hydroxyquinoline(5HQ),which can selectively detect nitrofuran antibiotics with lower detection limit and better anti-interference and cyclicality.2.Controllable encapsulation and release of complexes with fluorescent drug molecules as the guest.A case of porous complex(HNU-43)with a pore size of 13.5?×13.9?was synthesized by solvothermal method.Through the thermally driven(85oC)single crystal to single crystal(SC-SC)transformation,Zn-tsx with denser structure and smaller pore size were obtained.Using the change of the pores in the crystal structure transformation,the effective encapsulation of camptothecin(CPT)is realized with the loading of 11 wt%.The material loaded with CPT can gradually release CPT in a weakly acidic p H environment.Cell experiments confirm that the CPT-loaded material can stimulate release in the acidic microenvironment of hela cells and exhibit inhibition of cancer cells.3.Color and fluorescence adjustment of octanuclear zinc cluster complex.An octanuclear zinc cluster complex(HNU-53)was synthesized by the reaction of fluorescent ligand 5HQ with Zn²⁺.The crystals with different sizes of 200 nm-20?m were obtained by adjusting the reaction time.The electron spin resonance(ESR)test found that with the increase of the crystal size,the Austrian ripening process occurs,which gradually increases the defects in the crystal,which causes the generation of the crystal color center..Because of the existence of the crystal color center,the crystal size will change from colorless to red when the size of the crystal increase,and the fluorescence intensity will gradually decrease.In order to restore the crystal fluorescence,we introduced rare earth ions by in-situ method and found that the rare earth ions first formed a simple complex(Dy(5HQ)5DMF)with the ligand and solvent.Based on the principle of coordination competition and crystal growth,rare earth ion complexes The gradual disappearance in the solution slows down the growth of HNU-53 crystals,thereby reducing crystal defects,lightening the color,and turning on the fluorescence.