Research On Characteristics Of Composite Structure Of Zirconium-based Metallic Glass Surface In Pulse Laser Processing

In the amorphous alloy system,Zr-based amorphous alloys are widely used in medical implantation surgery because of their excellent mechanical properties and biocompatibility.However,the implant is a non-biological material,and the surface must be treated with active treatment before surgery to reduce the non-interlocking or even rejection reaction between the human body and the implant,and strengthen the biological regulation of the implant interface and dynamic tissue remodeling.Ensure the successful completion of the operation.Some traditional surface modification technologies achieve the improvement of biological activity by changing the surface morphology and roughness.This method is uncontrollable and cannot achieve overall consistency.In this paper,the method of combining pulse laser and chemical treatment is used to modify the surface activity of the implant.By immersing the simulated body fluid of the human body,the surface is deposited with biologically active hydroxyapatite,which is conducive to cell adhesion.Proliferation and differentiation are of great significance for improving the success rate of amorphous alloy medical implants.（1）The bionic design of the micro-nano structure on the surface of the implant.By analyzing the surface composition of the joints of human bones and bone joints,a bionic micro-nano structure was designed on the surface of the Zr-based amorphous alloy.By testing the surface microstructure under different parameters,the speed is too high or too small,the micro groove scanning is not uniform,the dot array or the energy excess makes the bottom of the groove mottled and undulating;the output power is too large or too small,and the groove boundary is splashed.,The molten material resolidifies at the bottom to make the depth shallow or the energy is not enough to prepare the depth required for the experiment.（2）Preparation of Zr₅₅Cu₃₀Ni₅Al₁₀ Zr-based bulk metallic glass composite micro-nano structure.Use the optimized laser parameters to process the required surface microstructure,and then use the configured strong acid solution to corrode the surface,which can process the composite microstructure combining the microgrooves and corrosion pits required for the experiment;The femtosecond laser scans linearly on the surface processed by the nanosecond laser to process two linear arrays of composite microstructures.（3）In vitro biological activity study of Zr₅₅Cu₃₀Ni₅Al₁₀ Zr-based bulk metallic glass composite structure.The increased hydrophilicity of the implant can improve the adhesion between the implant and the bone,thereby helping to regenerate damaged tissue in the body more quickly.The suitability and biological response of biological implants depend on its surface wettability,and wettability is a key factor affecting the performance of biological implants.The highly wettable surface facilitates the adsorption of specific proteins and minerals,thereby promoting a firm bond between the implant surface and the tissue.Industrial cameras were used to capture static contact angle images of different surface structures,and image analysis was performed with the measurement software Image J to observe and compare the wettability of different surfaces.The simulated body fluid of the human body contains ions necessary for the living environment of cells,among which Ca²⁺,HCO₃^―,HPO₄^2-plasmas can react to generate hydroxyapatite crystals necessary for bone cell attachment,and deposit them on the sample surface through immersion experiments.The content of hydroxyapatite is the main method for judging the biological activity of the surface of the material.Weigh the dried mass of the sample every three days,use SEM and EDS to analyze the surface HA deposition and element distribution,and compare the hydroxyapatite with different surface structures Stone nucleation rate and weight gain percentage,study the biological activity of different processing methods.（4）Electrochemical corrosion behavior test of Zr₅₅Cu₃₀Ni₅Al₁₀ Zr-based bulk metallic glass composite structure.Through Auto Lab electrochemical workstation,four groups of samples with different processing methods are used as working electrodes to obtain polarization curves and impedance spectra,analyze their corrosion potential and corrosion current density,and compare the corrosion speed and difficulty of different samples.Differences in surface biological activity modification technologies.Figure[39]table[7]reference[90]...