Study On Luminescence Sensor Based Of Coumarin And Its MOF Composite Material

In this paper,a fluorescent sensor for cysteine detection was designed and synthesized based on coumarin,and a composite material for detecting environmental pollution was synthesized using MOF as the frame material,at the same time,the fluorescence properties of the two materials were studied.The main content includes the following three chapters:The first chapter mainly introduces the research background of the related work of this thesis,briefly introduce the mechanism and advantages of fluorescence sensors in luminescent materials,the research progress of coumarin-based fluorescence sensors,and the research progress of existing metal-organic framework sensors;In the second chapter,a coumarin-based cysteine probe was designed and synthesized,and it was characterized by nuclear magnetic resonance,mass spectrometry,ultraviolet,fluorescence,etc.The study found that this probe can not only specifically identify Cys,and because we introduced a spacer group,it can also distinguish Cys,GSH and Hcy;In the third chapter,a luminescence metal-organic frame sensor has been designed and prepared that can effectively detect aromatic nitro compounds in water: coumarin-CAU-10(C-CAU-10),and we characterize its properties.CAU-10 is a porous aluminum isophthalate.Based on the mechanism of fluorescence quenching,this sensor can not only efficiently identify picric acid in deionized water environment,but also quantitatively detect picric acid in the range of 0-100μM.More importantly,this metal-organic frame sensor is suitable for the detection of picric acid in natural water.