Study On Visible Light Induced Difunctionalization Of Alkenes With Oxyimination

This paper is mainly divided into two parts.The first part briefly describes the research progress of nitrogen oxidation difunctionalization reaction of olefin in recent years.It mainly includes three aspects:(1)research on transition metal-catalyzed nitrogen oxidation difunctionalization reation of olefins;(2)research on metal-free catalyzed nitrogen oxidation of difunctionalization reation olefins;(3)research on visible light-catalyzed nitrogen oxidation difunctionalization reation of olefins.The second part mainly introduces the research on visible-light induced oxyimination of alkenes during the author’s master’s degree.mainly includes:The part details an intermolecular vicinal O-N difunctionalization reaction of olefins with oxime esters through energy transfer catalysis.In the process,oxime esters derived from aromatic carboxylic acids acted as bifunctional agents via the homolysis of O-N bond into two radicals.Then regioselective radical-radical difunctionalization of alkenes initiated with the O-centered radicals and terminated by the N-centered radicals.Additionally,the reaction induced by the iridium catalyst under blue LED irradiation without any assistance of external oxidant or reductant.The reaction can also be promoted under metal-free conditions with purple LED irradiation.This method is entirely atom-economic,step-economic and redox-economic.