Application Of Multi-mode Jet Ventilation In The Treatment Of Painless Fiberoptic Bronchoscope

Objective:To study the clinical effect of multi-mode jet ventilation and high-frequency jet ventilation in airway management of fiberoptic bronchoscopy under general anesthesia.Methods:40 patients of both sexes,aged 40-82 yr,with body mass index of18.4-29.1kg/m²,of American Society of Anesthesiologists physical statusⅠ-Ⅲ,scheduled for fiberoptic bronchoscopy under general anesthesia,were divided into 2 groups（n=20）by a random number table method:the high-frequency jet ventilation group（H group）and the multi-mode jet ventilation group（S group）.Group H adopted high-frequency jet ventilation and group S adopted multi-mode jet ventilation after general anesthesia with laryngeal mask.The HR,MAP,Sp O₂of vital signs,the PH value,the partial pressure of arterial oxygen（Pa O₂）and arterial carbon dioxide partial pressure（Pa CO₂）of arterial blood gas analysis were recorded after patients entering the operating room（T₀）,15min（T₁）and 30min（T₂）after high-frequency jet ventilation or multi-mode jet ventilation,restore spontaneous breathing immediately（T₃）,the concentration of Glu,C-reactive protein（CRP）,cortisol and interleukin-6（IL-6）were measured by enzyme-linked immunosorbent assay.The cases whose operation was suspended due to P_ETCO₂>80mm Hg were recorded.Results:Hyoxemia was not found in the two groups.Compared to T₀,HR increased at T_2,3in both groups,IL-6,Sp O₂and Pa O₂were increased at T_1³in both groups,In group H,MAP,blood glucose and cortisol increased at T_2,3,the p H value of group H decreased while Pa CO₂increased at T_1?3,CRP increased at T₃in group H,the p H value of group S decreased at T₂,MAP,blood glucose and cortisol increased at T₃in group S（P<0.05）.Compared with group H,HR and MAP were decreased at T₂,PH value was increased and Pa CO₂were decreased at T_1?3,blood glucose and cortisol and IL-6 were decreased at T_2,3,CRP was decreased at T₃in group S（P<0.05）.There are 3 cases in group H and 0 case in group S whose operation was suspended due to P_ETCO₂>80mm Hg.Conclusion:The multi-mode jet ventilation is superior to high-frequency jet ventilation in the airway management of painless fiberoptic bronchoscopy.