Analysis Of Clinical Efficacy Of Aerobic Exercise On Pcos Women

Objective: It’s important to get specified in the diet structure and exercise model to achieve an effective and efficient way of lifestyle intervention for patients with polycystic ovary syndrome(PCOS).Aerobic exercise was employed to figure out whether there are positive effects on patients with polycystic ovary syndrome,which is hoped to be supported by clinically feasible exercise data through changes in sex hormone levels and the metabolism of glucose and lipid.Method: For the First,literature analysis was conduct through metaanalysis.After reviewing the trails on exercise intervention for PCOS,closely related literature was selected and the possible therapeutic effects of exercise on PCOS were summarized on female sex hormones and metabolism of glucose and lipid.Meanwhile,a prospective cohort observational study was used.For patients with PCOS diagnosed in the outpatient clinic of the First Affiliated Hospital of Chongqing Medical University from 2019.09 to 2020.09 that were fully communicated in the real world were included in the aerobic exercise group(E,aerobic exercise),COC group(C,combined oral contraceptive),and combined treatment group(EC,COC combined aerobic exercise),which means the E group performs moderate-intensity aerobic exercises 3-4 times a week,and the COC group is in the oral administration of ethinyl estradiol and cyproterone tablets started on the 5th day of menstruation,and the EC group was treated by combination of the above.Exercise or medication time is 3 months,follow-up observation time is 3-6 months,and the main observation index are sex hormone indicators(FSH,LH,LH/FSH ratio,T,DHEAS)and glucose and lipid metabolism related indicators.The measurement data were tested by non-parametric rank sum test,and P<0.05 was considered as a statistically significant difference.Result: In the meta-analyze,the exercise group showed no improvement in the decrease of T,but improvement in the decrease of TC,LDL and increase of HDL,while it showed no significant association with BMI,and other metabolism index(glucose,insulin,TG,etc.).A small-scale cohort study carried out on this basis found out 34 patients came back and took examination after three months’ treatment.It can be found that the levels of female sex hormones in three groups improved to varying degrees after treatment.Among them,LH(-7.47(-15.65,2.15),P=0.025)and total testosterone(0.12(0.03,0.18),P=0.019)in E group decreased with statistical significance,indicating that exercise is similar in improving female sex hormones.However,there is no greater therapeutic effect in the combined treatment group.Considering that the treatment period is still short,there may not be a significant difference.The sex hormones and metabolic indicators between the groups were quite different due to the number of complete follow-up data in each group,and there was no significant statistical difference.Conclusion: The exact benefits of exercise for PCOS has not shown by literature analysis,which may be related to the inconsistency of exercise style,exercise intensity and exercise cycle.How to achieve a clinically effective method that is easy for patients to accept and adhere to is still unclear.A prospective cohort study designed based on this clinical problem began in 2019.It was confirmed in this cohort study that aerobic exercise can indeed improve female sex hormone levels in PCOS patients,and there may be similar improvement compared to drug treatment.Due to the bias of the sample size between groups,the proportion and importance of aerobic exercise in all aspects of PCOS treatment have not been obtained,and the changes in metabolism-related indicators are expected to be clarified in further research.