A Comparative Study Of Chest CT Imaging Between Connective Tissue Disease-associated Interstitial Lung Disease And Interstitial Lung Lesions Occur Secondary To Chronic Obstructive Pulmonary Disease

Objective:In this study,chest CT images of patients with connective tissue-related interstitial pulmonary disease(CTD-ILD)and Interstitial lung lesions occur secondary to chronic obstructive pulmonary disease(COPD)were compared and analyzed.The general character and distinction between them are revealed from the type of lesion,imaging signs,secondary and concurrent changes,lesion location,dispersion degree of lesion and disturbance degree of lung texture.In order to provides certain guidance for clinicians diagnose and distinguish interstitial lung lesions occur secondary to CTD and COPD.Methods: Analyze the chest CT of all research objects who were from the two affiliated hospitals of ours.Results:1.The prevalence is higher in women in the CTD group(P<0.05),and higher in men in the COPD group(P<0.05),the average age of patients in the COPD group is higher(P<0.05).2.The incidence of lung interstitial thickening is higher in the CTD group(P<0.05),and the incidence of pulmonary interstitial fibrosis is higher in the COPD group(P<0.05).3.The CTD group have the highest ground-glass opacity positive rate(37.70%),and higher than the COPD group(P<0.05);The positive rate of honeycomb shadow is the highest(42.0%),and including grid shadow,and strip shadow all are higher than CTD(P<0.05).4.The incidence of cystic changes,pulmonary artery thickening and pulmonary texture disorder in the COPD group are higher than CTD group(P<0.05).5.The incidence of interstitial pulmonary lesions in the lower lung field is highest in both groups(P>0.05),but the middle lobe is higher in the COPD group(P<0.05).6.The incidence of pulmonary interstitial lesions involving 2 lung lobes is the highest in the CTD group(P<0.05),but involving 4 lobes is the highest in the COPD group(P<0.05);The ratio of lesions involving 1 to 2 lobes is higher in the CTD group(57.54%)(P<0.05),but involving 4 to 5 lobes is higher in COPD group(61.93%)(P<0.05).7.The incidence of separate pleural thickening is higher in the CTD group(P<0.05),and higher in the COPD group with pleural thickening and adhesion(P<0.05).8.The ratio of bilateral pleural effusion is higher than that of unilateral pleural effusion in CTD group(P<0.05),there is no significant difference in the incidence of bilateral pleural effusion and unilateral pleural effusion in COPD group(P<0.05).Conclusion:1.CTD-ILD is most common in middle-aged female patients.The pulmonary interstitial lesions are mainly pulmonary interstitial thickening,and ground-glass opacity is the most common imaging signs.Most of the interstitial lesions are located in the lower lung field.The lung texture is clear,and there is few occur cystic changes and pulmonary hypertension.Simple pleural thickening is the main complication of pleural changes,and the incidence of pleural adhesion is low.Bilateral pleural effusion is the most common complication of pleural effusion.2.Interstitial Pulmonary lesions secondary to COPD are more common in older men.Interstitial fibrosis is the main lesion of the lung,and the developing signs showed a diversified trend,mainly including honeycomb shadow,mesh shadow,strip shadow,and honeycomb shadow is the most common.The lesions are mainly located in the lower lung and the periphery.The lung texture is more disorganized,the lesion is more diffuse,and prone to cystic changes and pulmonary hypertension.When the occurrence of pleural disease with pleural thickening and adhesion is significantly,there is no disparity in the incidence of unilateral and bilateral pleural effusion.