Clinical Application Of ABC Risk Score In Variceal And Non-variceal Upper Gastrointestinal Bleeding

Objective: To assess the clinical application of ABC score in predicting the prognosis of variceal（Variceal upper gastrointestinal bleeding VUGIB）and non-variceal upper gastrointestinal bleeding NVUGIB（NVUGIB）populations.Methods: Retrospective analysis of 172 patients hospitalized with confirmed upper gastrointestinal bleeding from October 2019 to March 2021,divided into variceal group（n=38）and non-variceal group（n=134）according to whether they were bleeding from ruptured veins,general clinical data were collected and ABC,AIMS65,GBS and CRS scores were calculated for the two groups respectively,ROC curves were drawn with blood transfusion,endoscopic intervention treatment,re-bleeding,in-hospital death and composite outcome as endpoints,and area under the ROC curve（AUROC）was compared between the two groups using the four scoring systems respectively.Results:（1）General information of patients in both groups was compared for albumin（t=4.222,P<0.001）,age（t=0.960,P=0.024）,systolic blood pressure（t=2.203,P=0.015）,INR（t=7.234,P<0.001）,ABC score（t=7.432,P<0.001）,AIMS65 score（t=5.234,P<0.001）,GBS score（t=4.792,P<0.001）,PRS score（t=5.707,P<0.001）were statistically significant,while there was no significant difference in the comparison of pulse rate,haemoglobin,urea and creatinine levels,and the proportion of patients in the VUGIB group requiring endoscopic interventions,death and blood transfusion was higher than that of The proportion of patients in the NVUGIB group who required endoscopic interventions,death and blood transfusion was higher than that of patients in the NVUGIB group.（2）Comparing the area under the ROC curves of the four scoring systems in the two groups,the ABC score was better than the AIMS65 score,GBS score and PRS score in predicting blood transfusion in NVUGIB patients（PABC-AIMS65=0.029,PABCGBS=0.033,PABC-PRS<0.01）,and in predicting in-hospital death in MVUGIB patients performance was comparable to the AIMS65 score and PRS score,statistically significant in predicting rebleeding in NVUGIB（AUROC=0.726,P=0.004）,and comparable to the AIMS65 score in predicting endoscopic interventions and in-hospital death in patients with VUGIB.Conclusion: The ABC score outperformed the existing UGIB score in predicting clinical outcomes associated with NVUGIB patients and was also valuable in predicting endoscopic interventions and in-hospital death in VUGIB patients.