Retrospective Study On The Regularity Of Syndrome And Treatment Of Reflux Esophagitis

Objective:The general data and clinical data of 176 patients with reflux esophagitis(RE)were retrospectively analyzed.The distribution regularity of syndrome types and the characteristics of medication were summarized.The objective and standardized exploration of TCM diagnosis and treatment of RE was carried out in order to better guide clinical practice.Methods:A total of 176 cases were included.The general data and clinical data of.the included cases were used to establish the related database of this project with Excel software.SPSS20.0 statistical analysis software was used to process and analyze relevant data.Frequency analysis and chi-square test were used.P<0.05 was considered statistically significant.Results:In this study,the ratio of male to female was about 1.44:1.The incidence was highest among middle-aged patients.Winter was the most common season for onset or aggravation(70 cases,39.8%).In terms of course distribution,patients with short course were the majority,and the patients with the course between half a year and three years were the most,accounting for 35.2%,followed by those with the course within half a year,accounting for 34.7%.Among the inducing factors,dietary factors and emotional factors were common.In the distribution of syndrome types,Liver-stomach Stagnation-heat Syndrome were the most(54 cases,30.7%),followed by of syndrome of blockade of dampness due to qi stagnation(37 cases,21.0%).There was no significant correlation between syndrome type and sex,age,disease or aggravating season.There were significant differences in the distribution of different genders in age group(P=0.004).It indicates that the difference in distribution of TCM syndrome type and disease course is statistically significant,and they are correlated(P=0.034).There was a significant difference in the distribution of TCM syndromes and incentives,and the two were correlated(P=0.000).Drug statistics showed that the top 20 most frequently used medicines were Pinellia ternata,Amomum villosum,Atractylodes macrocephala,Ginger,Aurantium aurantium,Coptis chinensis,Fritillaria thunbergii,Date,Butterfly,Tulip,Salvia miltiorrhiza,Radix Codonopsis,Licorice,Astragalus,Bupleurum,Bai ji,Xiebai,Trichosanthes,Evod ia rutaecarpa,Xiangfu,and the most frequently used medicines were Qi medicine,followed by Qingre medicine.Conclusion:The clinical syndrome differentiation and classification of RE are complex and diverse,with the majority of the patients suffering from syndrome differentiation,heat syndrome and liver-stomach diseases,and the most common is liver-stomach depression-heat syndrome.The pathogenesis is characterized by the discord between wood and earththe reversal of Qi in liver and stomach,the obstruction of Qi and blood,the stagnation of phlegm,the miscellaneous cold and heat,and the interaction of deficiency and reality.The treatment of this disease is mostly based on Regulating Qi and clearing heat,taking into account both tonifying qi and nourishing yin,resolving phlegm and dampness,inhibiting acid and reducing adverse reactions,activating blood circulation and removing blood stasis,and treating it according to syndrome differentiation.Clinical drug use closely around the spleen and stomach,hepatobiliary these two groups of viscera:mainly cold medicine,both with warm medicine,to Xin,bitter two flavor,with the harmony of Gan Medicine.