| purpose of researchTo observse the effect of yangxinshi on exercise intensity and quality of life of patients with ejection fraction preserving heart failure(HFpEF).methodsThis study was a single-center,randomized,single-blind study.A total of 74 patients with ejection fraction preserving heart failure(LVEF>50%)were included in the study(TCM syndrome differentiation:qi deficiency and blood stasis type or qi and Yin deficiency and blood stasis type),and they were divided into the experimental group and the control group according to the random number method.Two groups of patients in the standard of foundation treatment,western medicine group in this plan plus yangxin’s three months,the NT-proBNP level observed two groups of patients,6 minutes walking distance test,exercise tolerance and exercise intensity,improve heart function and TCM symptom integral change situation,the echocardiographic index changes,the sleep quality and the quality of life score,using SPSS 20.0 software for statistical analysis.Results(1)in the 6-minute walking test,the average walking distance of patients in the experimental group increased by 50m after treatment,and that of patients in the control group increased by 22m.After treatment,the average increase in exercise tolerance was 0.77METs in the experimental group and 0.48METs in the control group.The improvement in the experimental group was more significant than that in the control group,and the difference between the two groups was statistically significant(P<0.05).(2)after treatment,the level of nt-probnp decreased in both groups,with an average decrease of about 198.91pg/ml in the experimental group and an average decrease of about 214.97 pg/ml in the control group.The treatment was effective in both groups,and there was no statistically significant difference between the two groups after treatment(P>0.05).(3)cardiac echocardiography indicated that there was A significant difference in E/A between the two groups before and after treatment,and the difference was statistically significant(P<0.05).However,there was no difference in LA,LVEF,E/E’ value group or between the two groups,and there was no significant difference in E/A value between the two groups(P>0.05).(4)before and after treatment,the TCM syndrome scores of the two groups were significantly reduced,and the changes were statistically significant(P>0.05).There were significant differences between the two groups in the symptoms of palpitation,asthma,chills and spontaneous sweating(P<0.05).(5)the scores of quality of life were all improved compared with those before treatment,and the changes within the group were statistically significant(P<0.05).The experimental group showed significant improvement in emotional state,anxiety/depression,and the difference between the two groups was statistically significant(P<0.05).(6)after treatment,the PSQI scores of the two groups were reduced,suggesting that the sleep quality was improved,and the score of the experimental group was lower than that of the control group.The difference between the two groups was statistically significant.ConclusionYangxinshi short-term treatment may keep heart failure patients with mild increase ejection fraction 6 minutes walk test the longest distance and exercise intensity,speculated that long-term(>6 months)may improve cardiac function,type and correlation index keep heart failure patients with anxiety,depression,insomnia has obviously improved effect,moreover,can also improve the deficiency of blood stasis type or qi and Yin deficiency and blood stasis type of traditional Chinese medicine(TCM)clinical symptoms of heart failure patients(fatigue,heart palpitations,asthma,spontaneous perspiration),multidimensional to improve patients’ quality of life. |
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