The Effectiveness Of Using Prednisolone In Children With Community-Acquired Pneumonia

1.1 Objectives:1.Determine Prednisolone’s therapeutic impact in children aged 5 to 15.2.Examine the steroid’s side effects and medication dosage(prednisolone).3.Compare the length of stay in the hospital for patients who were cured with and without Prednisolone.1.2 Methodology:We retrospectively evaluated the effect of Prednisolone in 43 children with CAP who were admitted to the Infectious diseases of Andijon region(Uzbekistan)and made comparison with 46 children with CAP hospitalized in 2nd hospital of Shandong University(China)treated without Prednisolone.Outcome indicators were hospital stay,temperature and cough days of two group children.We used Prednisolone 30mg-1ml for intravenous/intramuscular use,manufactured by"Danica"(Ukraina),"Biopharma"(Ukraina)and "Gedeon Richter"(Hungary).1.3 Results:The mean age was 6.3 in China(Placebo)and 9.3 in Uzbekistan(control)years,54%and 52%of them were boys respectively.All children had received broad spectrum antibiotics(cephalosporin)or Macrolides(Azithromycin)and Oxygen.In addition to these we added Prednisolone 1 mg/kg on day 2 of admission to control group.24(68.5%from all febrile)children were became afebrile within 24 hours after Predisolone use on day 3 of admission,and their clinical status developed in control group,when it was achieved on day 7 in Placebo group.Hospital days also shortened in control group(6 days)than placebo(8 days)(p value≤0.01).1.4 Conclusion:Steroid therapy is helpful for reducing hospital stay and morbidity in children with community-acquired Pneumonia and no observed side effects.