Clinical Observation Of Jianpi Zaoshi Decoction In Treating Pi Xu(spleen Deficient)wet Type Functional Diarrhea

Objective: To observe the clinical efficacy and safety of Jianpi Zaoshi Decoction in the treatment of functional diarrhea of spleen deficiency and dampness,and provide theoretical guidance and new ideas for the clinical diagnosis and treatment of the disease in traditional Chinese medicine.Methods: This study included 62 patients who were treated in Dongge and Xianhu Districts of the First Affiliated Hospital of Guangxi University of Traditional Chinese Medicine from March 2020 to January 2021.All of them met the diagnosis of functional diarrhea by Western medicine.The type is spleen deficiency and dampness syndrome.The included cases were randomly divided into treatment group(Jianpi Dryshi Decoction group)and control group(Bifidobacterium triple viable bacteria capsule group).There was no significant difference in gender,age,course of disease,etc.between the two groups before treatment,and the dropped cases were excluded Thirty patients in the posttreatment group and 30 patients in the control group were treated for 4 weeks according to the treatment plan and followed up 4 weeks after the end of the treatment.Record the TCM syndrome scores of the treatment group and the control group before and after treatment,and observe the changes in the scores of each symptom,total effective rate,recurrence rate and safety of the two groups after treatment.Result:1.Comparison of the main and secondary symptoms of the two groups: After treatment,the total scores of TCM syndromes in the two groups were lower than before treatment,and the difference was statistically significant(P<0.05).The main symptoms and secondary symptoms in the treatment group were P<0.05 compared with those before treatment,and the difference was statistically significant;the main symptoms and secondary symptoms in the control group were fullness of the abdomen,lack of water,and bowel sounds compared with those before treatment.There was a statistical difference(P<0.05),but there was no statistically significant difference in limb drowsiness and mental status scores before and after treatment(P>0.05).It is suggested that the treatment group can well improve the main symptoms and accompanying symptoms of FDr patients with spleen deficiency and dampness,and the control group can improve stool characteristics,defecation frequency,fullness of the abdomen,lack of water,and bowel symptoms in FDr patients with spleen deficiency and dampness.However,the effect is not good for improving the patient’s limb drowsiness and mental condition.2.Comparison between the two groups: There was no statistically significant difference between the total scores of TCM syndromes and the scores of TCM single symptoms in the two groups before treatment(P>0.05).After treatment,the total scores of TCM syndromes between the two groups were compared,and the difference was statistically significant(P<0.05).After treatment,the treatment group and the control group were compared with the control group for fullness of the abdomen,lack of water,and bowel score,all P>0.05,the difference was not statistically significant;stool traits,defecation frequency,limb drowsiness,appetite,mental status score group Comparison between the two,all P<0.05,the difference is statistically significant.It is suggested that the treatment group is better than the control group in improving clinical symptoms.The treatment group is better than the control group in improving stool characteristics,defecation frequency,limb drowsiness,appetite,and mental status after treatment.The treatment group and the control group are better than the control group after treatment.The curative effect is equivalent in terms of non-removal of water and intestines.3.Effective rate analysis: the total effective rate of the treatment group is 90%;the total effective rate of the control group is 66.7%.The difference was statistically significant(P<0.05),indicating that the treatment effect of the treatment group was better than that of the control group.4.Comparison of recurrence rate: The recurrence rate of the treatment group was 13.3%,and the recurrence rate of the control group was 53.3%.After Chisquare test,the difference was statistically significant(P<0.01),indicating that the long-term curative effect of the treatment group was better than that of the control group.5.Safety: During the treatment process,the two groups of patients had no obvious adverse reactions and toxic side effects,and no obvious symptoms of discomfort,indicating that this treatment plan is safe and effective in the treatment of functional diarrhea.Conclusion:1.Jianpizaoshi decoction can effectively improve the clinical symptoms of patients with functional diarrhea of spleen deficiency and dampness.2.To treat functional diarrhea of spleen deficiency and dampness type,Jianpi Dampness Decoction and Bifidobacterium Triple Live Bacteria Capsules are both safe and effective treatment options.In terms of clinical efficacy,Jianpi Dashi Decoction is significantly better than Bifidobacterium triple live Bacteria Capsule,And can effectively reduce the recurrence rate.