Evaluation Of Clinical Curative Effect Of Acupuncture And Medicine Combined Therapy On Anterior Ischemic Optic Neuropathy

Objective: By observing the effects of the combination of acupuncture and medicine on the visual acuity,visual field indicators and the thickness of the optic nerve fiber layer in patients with non-arteritic anterior ischemic optic neuropathy,the clinical efficacy of the disease can be evaluated.It provides a theoretical basis for the clinical application and research of acupuncture combined treatment of anterior ischemic optic neuropathy.Methods: The 88 NAION patients(170 eyes)were randomly divided into three groups,56 eyes in the compound anisodine injection group,58 eyes in the acupuncture + compound anisodine injection group,and acupuncture + anisodine hydrobromide tablets group 56 eyes cases.The treatment plan for the injection group is: give compound anisodine injection treatment,take 2ml of the drug and inject it subcutaneously next to the superficial temporal artery of the affected eye,once a day;the treatment plan for the acupuncture + injection group is: based on the injection group Ascending acupuncture treatment;the treatment plan of the tablet + acupuncture group is: acupuncture is the same as before,and the medicine is taken orally 1 mg anisodine hydrobromide tablets twice a day.The course of treatment is 2 weeks.Record and compare the data before and after treatment of the two groups of patients: visual acuity,intraocular pressure,visual field(MD,VFI),optic nerve fiber layer(RNFL)thickness,disease efficacy,and safety indicators,and perform statistical analysis.Results: 1.Before treatment,the differences in gender,age,course of disease,visual acuity,visual field index,average visual field defect,and optic nerve fiber layer thickness were not statistically significant,and they were all comparable(P>0.05).2.Visual acuity: Compared with before treatment,the eyesight of the three groups of patients improved after treatment;but the compound anisodine injection group,acupuncture +compound anisodine injection group were more significant.3.MD: Compared with before treatment,the MD values of the 3 groups of eyes were significantly decreased after treatment,and the differences were statistically significant(P<0.05);and the acupuncture + anisodine hydrobromide tablets group was better than acupuncture + The compound anisodine injection group had a more significant effect on improving MD(P<0.05).The remaining groups are relatively meaningless.4.VFI: Compared with before treatment,the visual field index of the three groups was significantly improved after treatment(P<0.05);and the visual field index of the acupuncture+ compound anisodine injection group was higher than that of the simple compound anisodine injection group The degree of improvement is more significant(P<0.05).The remaining groups are relatively meaningless.5.RNFL: Compared with before treatment,the RNFL thickness of the three groups of patients increased after treatment(P<0.05);but the comparison between the three groups was meaningless(p=0.417>0.05).6.Evaluation of disease efficacy: After treatment,the total effective rates of acupuncture+ compound anisodine injection group,compound anisodine injection group,and acupuncture+ anisodine hydrobromide tablets group were 71.43%,65.52 %,68.97%;7.Safety: After treatment,the intraocular pressure,blood pressure,heart rate,liver and renal function of the 3 groups of patients were all within the normal range,and there was no obvious abnormality,and there were no obvious adverse reactions in the 3 groups.Conclusions: 1The treatment methods of the group can improve the visual function of non-acute NAION patients and improve the curative effect.2.Acupuncture + compound anisodine injection is more helpful to improve the VFI of non-acute NAION patients than simply using compound anisodine injection.3.Acupuncture + compound anisodine injection group is more helpful to improve the MD of non-acute NAION patients than the acupuncture + anisodine hydrobromide tablets.