Risk Factors Of Deep Venous Thrombosis Syndrome After Iliac Vein Stent Implantation In Patients With DVT Complicated With Cockett Syndrome

Objective:To investigate the risk factors of post-thrombotic syndrome(PTS)in patients with deep venous thrombosis(DVT)and Cockett syndrome after iliac vein stent implantation.Methods:The medical records of 46 patients with DVT combined with Cockett syndrome and iliac vein stenting implantation in the Department of Vascular Surgery were included in this retrospective study,who visited the Third Affiliated Hospital of Nanchang University from January 2016 to February 2020.At 12 months,duplex ultrasound or antegrade venography was performed to assess the iliac femoral vein patency and deep venous reflux,and post-thrombotic syndrome was assessed using the Villalta score table.The patients were divided into PTS group(experimental group)and non-PTS group(control group).The data were analyzed by?2 and multivariate unconditional binary logistic regress analysis to determine the risk factors of deep venous thrombosis syndrome of lower extremities.Results:The forty-six patients were included 21 males and 25 females,who were aged(59.71±17.58)years and BMI(23.35±2.63)kg/m~2.Follow-up was 12 months,and post-thrombotic syndrome developed in ten patients(21.7%),the Villalta score of PTS patients(5.4±0.7).Three variables associated with PTS after iliac vein stent implantation in DVT patients were screened atα=0.05 level,which were BMI≥24kg/m~2(P=0.006),course of disease>2 weeks(P=0.047),calf muscle thrombosis(P=0.020),P<0.05,and the difference was statistically significant.The three significant variables were analysed by multivariate unconditional binary logistic regress analysis.At the level ofα=0.05,the major risk factor who suffer from DVT combined with Cockett syndrome and iliac vein stenting implantation is BMI≥24 kg/m~2(OR=6.350,CI=1.082-37.260),P<0.05,and the difference was statistically significant.Conclusion:BMI≥24.0 kg/m~2is a major risk factor for PTS in DVT patients with Cockett syndrome after iliac vein stent implantation.After surgery,DVT patients can effectively reduce the risk of PTS by controlling body weight,standardizing anticoagulation and pressure socks.