A Study On The Association Between Recurrent Respiratory Tract Infection And Obesity And Vitamin D Levels In Children

OBJECTIVE:To investigate the relationship between repeated respiratory infections and obesity and vitamin D levels in children with obese children with recurrent respiratory infections.METHODS:A total of 184 children with respiratory infection who were hospitalized in the pediatrics department of the First Affiliated Hospital of Dalian Medical University from January 2018 to December 2018 were enrolled.The 184children were divided into groups.The experimental group was 84 children with repeated respiratory infections,and the control group was 100 children with common respiratory infections.The first is using the single factorx~2test and multivariate logistic regression analysis to analyze whether vitamin D and other laboratory test indicators increased the risk of recurrent respiratory infections;the second is using Pearson correlation analysis method to analysis the relationship between BMI and vitamin D in children with recurrent respiratory infection,that is,whether BMI and vitamin D synergistically increase the risk of repeated respiratory infection in children;and the third is comparing the vitamin D,immune index and lipid index of experimental group and control group by using t test,body fluid immune indicators include Ig A,Ig G,Ig M,and cellular immune indicators including Ts/Th,NK cells,and lipid indicators including TG,TC,LDL,and HDL.RESULTS:The first,by using the single factorx~2test and multivariate logistic regression analysis,it is found that elevated BMI and decreased vitamin D were risk factors for repeated respiratory infections.The second,pearson correlation analysis showed that BMI was associated with vitamin D.,and the r value was-0.784,it means moderately correlated;the third by t test,the experimental group Ig A,BMI and vitamin D levels were lower than the control group,P<0.05,with statistical difference;CONCLUSION:The first is that decreased serum vitamin D levels and obesity may be independent risk factors for repeated respiratory infections;the second is thatobesity and decreased serum vitamin D levels synergistically increase the risk of repeated respiratory infections in children.