A Retrospective Study Of Zicao Yanghe Decoction Combined With Surgery In The Treatment Of Non-lactation Mastitis

Objective:The purpose of this study is to evaluate the safety,effectiveness,degree of satisfaction and recurrence of the patients with non-puerperal mastitis by using the combined operation of purple grass Yanghe Decoction in the treatment of non lactating mastitis,and to provide more effective treatment for non-puerperal mastitisMethods:From 2015.09to2017.12,the medical records of patients with non-puerperal mastitis and TCM syndrome and sores were diagnosed.According to the exclusion criteria,the patients were divided into two groups based on the treatment plan of the patients:the patients receiving the combined operation of purple grass Yanghe Tang were treated as the combined treatment group;the surgical incision was performed alone.The drainage group was treated by incision and drainage.Statistical analysis of the general situation of two groups of patients,and further analysis of the two groups of patients after different ways of treatment,the difference in TCM syndrome improvement,cure rate,recurrence rate,patient satisfaction and so on.The safety of operation was evaluated by operative time,intraoperative blood loss and postoperative healing.Results:A total of 49 patients who met the inclusion criteria were all female.Among them,31 cases were combined treatment group,18 cases were incision and drainage group.The age of two groups was in normal distribution.The mean age was(?),which was 34.73+4.872 years old,P>0.05.There was no difference in age between the two groups.The size of the tumor did not conform to normal distribution,the combined treatment group was 5.74(4.5,7)cm,the control group was 5.64(4,7.25)cm,non-Reference test,P>0.05,there was no difference between the two groups,and there was no significant difference between the combined treatment group and the control group before treatment.The symptom score before treatment,non parameter test,P>0.05,there was no statistical difference between the two groups,that is,the symptoms of the two groups were roughly equal before the combined treatment group and the control group.The incidence of ductal lesions was 36.7%,the use of anti psychotropic drugs with contraceptive drugs was 14.3%,the high expression of prolactin was 2%,and the abnormality of autoimmunity was 18.4%.The pathogenic examination of pyogenic fluid(aerobic+ anaerobic)culture was negative.Of the 49 patients enrolled,48 had fertility history,47 of whom had lactation history.There were 18 cases of lactation disorder during lactation.And it happens more than 4-6 years after breast-feeding.Most of the lesions were unilateral,and 3 of 49 patients had bilateral lesions.The other 46 cases were unilateral,and there was no significant difference in the incidence of bilateral diseases.In 49 patients,5 cases had erythema or nodules in lower extremities.In terms of operative safety evaluation,there were no malignant adverse events in 31 patients in the combined treatment group.Preoperative peripheral blood leucocytes were higher than normal level in 1 patients,and normal after operation.The white blood cells of the remaining 30 patients were normal before and after operation.The liver and kidney function of 31 patients were normal before and after operation.The average time of operation was 143.6(130,160)minutes,the average bleeding amount was 136.1(100,200)ml,the average drainage time was 5(4,6)days after operation,and the average time of postoperative disassembly was 11.48(11,13)days.The patient healed in one phase.No postoperative breast union occurred and patients with infection in operation area.In this study,49 patients in symptomatic improvement were examined by X2 test and P<0.01.There was significant difference between the two groups.That is,the combined treatment group is obviously better than the control group.In the recurrence rate,the recurrence rate of the combined treatment group was 0,X2 test,P<0.01,the recurrence rate of the two groups was significantly different,and the recurrence rate of the combined treatment group was significantly lower than that of the control group.In the breast shape evaluation,the Harris standard was used.After the rank sum test,the two groups were P>0.05.There was no statistical difference between the two groups,that is,there was no significant difference in the shape of the breast in the patients with the glandular resection compared with those in the non glandular resection.JCRT standard was used for patient satisfaction evaluation.After rank sum test,the two groups were P<0.01.There were significant differences between the two groups,that is,the satisfaction of the combined treatment group was significantly higher than that of the control group.The Vancouver scar scale was used in the evaluation of scar.The(?)in the combined treatment group was 3.45+0.96,the control group was 6.72+2.81,T test,P<0.01,and the two groups had significant difference.The scar in the combined treatment group was lighter than the control group.Conclusion:1.Shikonin Yanghe Decoction Combined with surgery in the treatment of Yin Syndrome of non lactation mastitis treatment method is safe and reliable.2.The combination of shikonin Yanghe Decoction and operation in the treatment of Yin Syndrome is not effective for lactation mastitis.The treatment cycle is short,the recurrence rate is low,and it is effective.It is worthy of further promotion after clinical examination.