| With the development of informatization technology in healthcare and the promotion of national policies,the number of information systems and decision support systems in hospitals are gradually increasing.There are two means on how hospitals adopt decision support services: firstly,the hospital needs to participate in the construction and maintenance of the decision support knowledge base;secondly,the hospital is the receiver of the decision support service provided by the manufacturer.As many different kinds of business exist in a hospital,the interaction between multiple information systems is quite often in daily practice.Due to the heterogeneity between multiple systems provided by different manufacturers,there are mainly two problems: it is difficult to migrate the existing knowledge base to a new base,and the service connecting process is quite complicated and cumbersome due to the lack of a scientific and reasonable coordination mechanism.To deal with these two problems,this thesis studies the method for integrating different knowledge bases which supports updating integrated knowledge in real time.On this basis,the decision support center was designed and developed,and a case study was carried out for the interface calling of services such as rational drug use knowledge integration,outpatient and resident doctor workstations,and inspection and testing rationality.The main contents are as follows:1.Design and construct a knowledge base for the decision support center.By analyzing the structure of drug instructions and rational drug use manufacturers’ knowledge base,an E-R diagram is constructed to represent the basic knowledge of drugs and the collaborative relationship between knowledge.Based on Object Relational Mapping(ORM)technology,a knowledge base table structure is generated to store the contents of different manufacturers’ knowledge bases.2.Design and implement a knowledge update mechanism.Based on the data transmission function in the integration engine,when the content of the manufacturer’s knowledge base changes,the updated knowledge content of the manufacturer can be synchronized to the knowledge base in the decision support center through the Database Reader/Writer,HTTP Request,and File Write functions of the integration engine’s channel.3.Specify the interfaces for workflow calling.Referring to the IHE(Integrating the Healthcare Enterprise)technical framework,this thesis standardizes the interface invocation process for services such as rationality of hospital inspection and testing,disease derivation,and interpretation of test results,and sort out the interface parameters.Redesign the Web service interface required to invoke multiple services.Carry out the practice of this system in the actual medical environment of a tertiary hospital in Shanxi.The knowledge base of the Decision Support Center integrates 5525 drugs,10 rational drug use rules,and 5443 drug instructions from 2 rational drug use manufacturers,and achieves real-time updates of drug instructions.Secondly,after the decision support center integrates multiple decision support services,the concurrency performance of the decision support center interface is tested.When the number of accesses to the interface at the same time is less than 10,the response time of the interface can be stable within 2.0 seconds,which can meet clinical needs. |