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Studies On The Imaging Diagnosis Of The Coenurus Cerebralis In Sheep

Posted on:2022-11-29Degree:MasterType:Thesis
Country:ChinaCandidate:W DengFull Text:PDF
GTID:2543307133984599Subject:Clinical Veterinary Medicine
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Coenurus cerebralis currently lacks a rapid and accurate diagnosis method,similar to other animals,the clinical symptoms of sheep with coenurus cerebralis depend on the location of the lesion in the brain and the course of the disease,but the clinical symptoms do not provide a good indication of the cause.As a result,pathological necropsy is still the gold standard for the diagnosis of the coenurus cerebralis.In medicine,medical imaging has become the gold standard for diagnosing coenurus cerebralis,and medical 3D reconstruction is the current research hotspot.Therefore,this study uses MRI,CT,and medical 3D reconstruction technology to carry out related research on the anatomical structure of goat’s brain,head,and sheep coenurus cerebralis,aiming to promote the application and development of medical imaging in economic animals and provide reliable references to relevant staff.A 16-slice spiral CT scanner was used to scan the head of 6 goats to obtain crosssectional images,and then obtain sagittal and coronal images through multi-planar reconstruction.A 1.5T superconducting magnetic resonance scanner was used to scan the brains of 6 goats.The scan sequence included the spin echo(SE)T1 sequence and the fast spin echo(FSE)T2 sequence.The scan slices included the sagittal,transverse,and coronal planes.The obtained image was annotated with Photoshop for anatomical structure.The study obtained a complete set of the the CT and MRI imaging maps of the goat’s head.It provided reference materials for in-depth understanding of the image anatomy of the goat’s head and brain,and also provides normal reference images for goat’s head disease.In this experiment 2,4 cases of sheep showing neurological dysfunction were collected,neurological examination,laboratory examination,and pathological necropsy were performed and finally diagnosed as coenurus cerebralis.The results showed that there are some differences in the neurological symptoms of sheep coenurus cerebralis.The autopsy revealed that there were cysts filled with clear fluid in the animal’s brain,and there were clusters of white punctate protoscolices on the cyst wall,widened cerebral sulci and gyrus were observed in the cerebral hemisphere where the parasitic cysts located.Histopathologically,there was a large area of necrosis in the brain tissue around the cyst can be observed,as well as decreased Purkinje cells,loose and broken white matter fibers,and abnormal pathological changes such as infiltration of a large number of monocytes and multinucleated giant cells.The protoscolices can be divided into cortical layer and parenchymal layer,the cortical layer was composed of microvilli and syncytium,the parenchymal layer include muscle tissue.The front end of the protoscolices was the rostellum,which contained a sucker and small hooks.The hook has a refractive,curved conical or comma-like structure;The sucker is composed of a sucker membrane,muscle fibers of sucker,membrane of fissure and Fissure in the sucker in order from the outside to the inside.CT and MRI scans were performed on 3 cases of sheep coenurus cerebralis,and medical3 D reconstruction was performed.The aim of the study was figure out the imaging characteristics of coenurus cerebralis and the application of medical 3D reconstruction in the field of veterinary medicine.On CT images,parasitic cysts showed cystic hypoattenuating images,and the protoscolices showed punctate hyperattenuating images.On MRI images,parasitic cysts showed cystic lesion with low signal on T1 WI and high signal on T2WI;The protoscolices showed equisignal T1 WI and low signal on T2 WI.In addition,through imaging examination,abnormal imaging changes such as the thinner inner layer of the skull bone around the lesion,hydrocephalus can also be observed.Through imaging examinations,the location of the lesion can be accurately located,the number of lesions can be determined,and assessed the involvement of adjacent organs.The 3D model reconstructed from the twodimensional image of the case can observe the lesion in all directions;and the lesion can be visualized and intuitive through transparent processing,which is beneficial to the veterinarian to formulate a comprehensive surgical plan.
Keywords/Search Tags:Ovine, Coenurus cerebralis, Magnetic resonance imaging, Computed tomography, 3D reconstruction
PDF Full Text Request
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