Observation On The Curative Effect Of Qingrezhitengsan In The Treatment Of Herpes Zoster With Stagnant Heat In The Liver Meridian

Objective: To observe the efficacy and safety of external application of Qingrezhitongsan combined with western medicine in the treatment of herpes zoster with stagnant heat in the liver meridian and observe the clinical application value of Qingrezhitongsan.Method:A total of 80 patients from December 01,2020 to November 30,2021 in the outpatient and inpatient departments of Haiyang Traditional Chinese Medicine Hospital who met the inclusion rules were divided into a treatment group and a control group according to the random number table method,with40 cases in each group.The treatment group was given western medicine antiviral treatment + nutritional nerve treatment + Qingre Zhiteng San,while the control group was given western medicine antiviral treatment + nutritional nerve treatment+ Acyclovir cream topical treatment for 7 days.According to the Statistics and observation of the two groups of patients before and after treatment of nerve pain intensity,pain relief time,pain complete disappearance time and blister,scab,scab removal time,the incidence of postherpetic neuralgia and other indicators,data was statistically analyzed,and then evaluate the clinical efficency of two treatment method.Results:(1)There was no significant difference in the time of pain relief between the two groups(P>0.05).(2)The pain subsidence time between the two groups was statistically significant(P<0.05),and the pain subsidence time in the experimental group was shorter than that in the control group.(3)There was a statistically significant difference in the anti-blistering time between the two groups(P<0.001),and the anti-blistering time in the experimental group was significantly shorter than that in the control group.(4)The time of scab formation between the two groups was significantly different(P<0.001),and the scab formation time of the experimental group was significantly shorter than that of the control group.(5)There was no significant difference between the two groups in terms of treatment time for exfoliation(P>0.05).(6)There was a statistically significant difference between the two groups in the treatment effective rate(P<0.01),and the treatment effective rate in the treatment group was significantly higher than that in the control group.(7)There was no significant difference between the two groups in the treatment effects(P>0.05),and there was no significant difference in the treatment effect between the experimental group and the control group.(8)The incidence of postherpetic neuralgia in the experimental group was lower than that in the control group.(9)The pain relief time was negatively correlated with the scabbing time;the pain subsidence time was positively correlated with the blister-stopping time and scabbing time,and negatively correlated with the effective rate and treatment effect;the blister-stopping time and the scab removal time were significantly negatively correlated with the effective rate and significant negative correlation with the treatment effect;the time of scab formation was significantly positively correlated with the time to stop the blister;the occurrence of postherpetic neuralgia was significantly positively correlated with the time of scab formation and scab removal.Conclusion: The external application of Qingre Zhitong San combined with western medicine in the treatment of herpes zoster patients with liver meridian stagnation heat type herpes zoster is more effective than the simple western medicine treatment,the incidence of postherpetic neuralgia is lower,the pain subsidence time is shorter,and the scabbing time and Blister time.Qingrezhitongsan can reduce the incidence of postherpetic neuralgia and relieve the pain of patients.