Predictive Value Of China Acute Myocardial Infarction For Non-ST-segment Elevation Myocardial Infarction Score Combined With High Sensitive Cardiac Tropon T In Patients With Acute Non-ST Elevation Myocardial Infarction

Aim:To investigate the value of china acute myocardial infarction for non-ST-segment elevation myocardial infarction(CAMI-NSTEMI)score combined with high-sensitivity troponin T(hs-c Tn T)in predicting prognosis of patients with acute non-ST segment elevation myocardial infarction(NSTEMI).Methods:A total of 342 patients with NSTEMI diagnosed in Fenyang Hospital Affiliated to Shanxi Medical University from September 2018 to December 2020 were selected.Their clinical data were collected and grouped according to whether major adverse cardiovascular events(MACE)occurred or not.Compared the differences of baseline data、serum concentration of hs-c Tn T and CAMI-NSTEMI score between the groups and evaluated the correlation between serum concentration of hs-c Tn T 、 CAMI-NSTEMI score and MACE.MEDCALC statistical software was used to draw ROC curve and compared the area under the curve to analyze the prognostic efficacy of each index for NSTEMI patients.Results:1.Compared with the non MACE group,the leukocyte count,neutrophil absolute value,platelet count,serum creatinine,fasting blood glucuse,serum concentration of hs-c Tn T and CAMI-NSTEMI score in MACE group were significantly higher,and the levels of systolic blood pressure,systolic blood pressure and hemoglobin were significantly lower(P < 0.05).2.Correlation analysis showed a positive correlation between CAMI-NSTEMI risk score and serum hs-c Tn T concentration(R = 0.401,P < 0.001).3.Multivariate logistic regression analysis showed that serum concentration of hs-c Tn T and CAMI-NSTEMI score were independent predictors of MACE in NSTEMI patients(P < 0.05).4.ROC curve analysis showed that the AUCs predicted by serum concentration of hs-c Tn T and CAMI-NSTEMI score for MACE were 0.784、0.797,the cut-off values were 180 and 89.5,respectively,the sensitivity was 0.941 、 0.824,the specificity was0.515、0.711.After the combination of the two groups,the area under the curve was 0.854,the sensitivity was 0.941,and the specificity is 0.67.There was no statistically significant difference in AUC between groups(P > 0.05).Conclusion:In NSTEMI patients,serum concentration of hs-c Tn T and CAMI-NSTEMI score are independent predictors of MACE,and CAMI-NSTEMI score combined with serum concentration of hs-c Tn T can predict the occurrence of MACE in NSTEMI patients.But it did not demonstrate predictive value superior to CAMI-NSTEMI score alone or serum concentration of hs-c Tn T.