The Value Of MRI In Differentiating Intracranial Solitary Fibrous Tumor From Hemangiomatous Meningioma

Objective:To investigate the value of MRI in the diagnosis and differential diagnosis of intracranial solitary fibrous tumor(SFT)and angiomatous meningioma(AM).Methods:The preoperative magnetic resonance imaging data of 100 SFT patients and 117 AM patients confirmed by surgery and pathology were retrospectively collected.Combined with the following main sequences of MRI,T1 WI,T2WI,DWI,T2 FLAIR,and T1WI+C Using the RADIANT dicom viewer software,the region of interest(ROI)was manually delineated from the axial image,and imaging features were extracted and screened,and imaging parameters were measured.Signal value,using the ratio of the two measured values to calculate the normalized ratio N(normalized ratio),which are NT1WI(normalized ratio T1WI),NT2WI(normalized ratio T2WI),NT2F(normalized ratio T2FLAIR),NDWI(normalized ratio DWI),NT1 + C(normalized ratio T1WI+C).Quantitative analysis of standardized ratios.The image characteristics and standardized ratios were analyzed by statistical methods such as T test and chi-square test of two independent samples,and the multivariate logistic regression model was used to further analyze and evaluate whether the above image characteristics and standardized ratios could predict the occurrence of SFT.The receiver operating characteristic(ROC)curve was drawn to evaluate its differential diagnosis performance for SFT and AM.Results:(1)The T test of two independent samples showed that the age(55.11±12.11 vs46.10±13.99,P<0.001),size(49.28±48.70 vs 91.70±89.30,P<0.001),NT1 WI of patients in AM group and SFT group(0.59±0.22 vs 0.84±0.18,P<0.001),NT2WI(2.06±0.55 vs1.51±0.34,P<0.001),and NDWI(1.52±0.53 vs 1.15±0.40,P<0.001)had statistical differences study meaning.(2)The independent sample T test for peritumoral edema found no significant difference between AM and SFT(t=-0.544,p=0.125).(3)Chi-square test was performed on the enumeration data,and it was found that AM and SFT vascular flow voids(X2=17.944,P=0.000)and bone destruction(X2=9.766,P=0.002)had statistically significant differences,while the meningeal tail had statistically significant differences.There was no significant difference between AM and SFT(X2=0.965,P=0.326).(4)Multivariate Logistic regression model analysis showed that age,NT1 WI,NT2WI and vascular flow void were independent predictors of SFT(P=0.040,OR: 0.91,CI: 0.831-0.996;P<0.001,OR: 3334.942,CI : 41.229-269758.213;P=0.006,OR: 0.003,CI: 0.000-0.188;P=0.039,OR: 15.89,CI: 1.145-220.453).(5)For the SFT predicted by NT1 WI,the area under the ROC curve was 0.862,the diagnostic threshold was 0.7513,the sensitivity was 76.6%,and the specificity was 85.7%;the AM predicted by NT2 WI,the area under the ROC curve was 0.802,the diagnostic threshold was 1.7425,and the sensitivity was 0.802.The specificity was 70.5% and the specificity was 79.5%.Conclusion:MRI is of great value in differentiating SFT from AM.Age,NT1 WI value,NT2 WI value,and vascular flow void are independent predictors of SFT.Patients with higher NT1 WI value and lower age and NT2 WI value have higher risk of being diagnosed with SFT.