Study On The Effects Of Exercise Rehabilitation Therapy On Correlation Relationship Between Cardiorespiratory Function And Anxiety And Depression Score In Patients After PCI

Background:The death toll dying from Cardiovascular Diseases（CVD）in China continues to grow with each passing year,and the prevalence rate assumes year by year,and CHD,one of the principal forms of CVD,has become the leading cause of death worldwide,hence cardiovascular disease prevention and treatment allows of no delay.A duration of three decades of development renders PCI into the most important method for CHD therapy in China.Although PCI can bring symptoms relief,patients after PCI still face many problems,and lays the burden on families and society.At present,clinical attention is focused on the query of how to reduce the risk of adverse events after PCI,as well as the enhancement of motor function,anxiety,and depression in postoperative patients.Objective:This trial assessed the cardiopulmonary function as well as anxiety and depression status of patients after PCI by means of CPET examination,GAD-7 and PHQ-9 score scale.The purpose of this research is to assess the influence of cardiac exercise rehabilitation therapy on cardiopulmonary performance and the anxiety and depression levels of those who have undergone PCI.Method:1.Object selectionSubjects were selected from a total of 166 patients who were treated for CHD and underwent both CPET and PCI surgery from October 1,2021 to June 31,2022.Randomly divide patients into rehabilitation group and control group.Excluding 5withdrawal cases,the rehabilitation group had 80 cases,while the control group had 81cases.The ethics committee of the hospital gave their approval to this study program,and all patients consented to the informed consent process prior to PCI and CPET examinations.All the enrolled cases were confirmed by two deputy chief physicians or above,which met the inclusion criteria and exclusion criteria.Collection of relevant information includes age,gender,BMI and things like that.Absolute and relative contraindications associated with cardiopulmonary exercise testing,active bleeding,severe liver and kidney dysfunction were not included in this study.2.Experimental methodRelevant disease health education was conducted for all selected patients after PCI,and drug treatment of CHD and other basic diseases were optimized.Scientifically formulated exercise prescriptions suitable for patients,were given to those in the rehabilitation group for a period of 6 months.Monthly follow-up visits were conducted through outpatient clinics and telephone calls to understand the general situation of medication and exercise of the two groups of patients,and the treatment plan could be adjusted appropriately according to their own situation.Revisit was scheduled after 6 months to check for changes in relevant indicators.If patients feel unwell during exercise,exercising ought to be stopped and medical attention needs to be sought if necessary.The trial could be terminated at any time upon patients’wishes.3.Statistical methodsThe research was analyzed adopting SPSS26.0 software in order to test statistical differences.The data of the normal distribution were expressed in the form of"±S",and the data of the non-normal distribution were represented using the median M（p25,p75）.Composition ratio is used to illustrate the count data.For the data of normal distribution,t-test or one-way ANOVA was used for the comparison between groups;The difference before and after the group met the normal distribution,and paired sample t-test was used;For non-normal distribution measurement data,Wilcoxon rank sum test or Kruskar-Wallis test shall be used for inter-group comparison,and Wilcoxon signed rank test shall be used for intra-group comparison if the difference before and after the group does not meet the normal distribution;Chi-square test was used to compare the constituent ratio of the counting data.With the rehabilitation group as the dependent variable,the variables with a single factor P<0.05 were screened and brought into the multivariate logistic regression to explore the specific relationship between rehabilitation treatment and various influencing factors.The correlation between P<0.05 was statistically significant.Result:1.After 6 months of treatment,the Peak W、Peak W%pred、ΔVO₂/ΔWR、VO₂/kg@AT、Peak VO₂/kg%pred、METs@AT、Peak VO₂/kg、Peak METs%pred、Peak METs、O₂-pulse@AT、Peak O₂-pulse%pred、Peak O₂-pulse in the exercise group were increased than those before treatment,while the corresponding indicators of the control group were decreased and the difference was statistically significantbefore and after treatment.After treatment,the Peak HR、Peak HR%pred in the exercise group were lower than those before treatment,while the corresponding indicators of the control group were significantly increased,and the difference was significant before and after treatment（P<0.05）.2.After 6 months of treatment,the FEV1.0%,T%,W@AT and Peak RER in the exercise group were augmented in comparison to before treatment,while the numerical values of SBP@AT,DBP@AT,Peak DBP,HR@AT and HRmax-HR1min were reduced.The difference between the two groups was significant（P<0.05）,yet the difference in the control group’s corresponding indicators was not found to be significant（P>0.05）.3.Compare the discrepancy betwixt the D-value of GLU、SCR、BUN、α1-MG、GFR、FEV1.0%、T、W@AT、Peak W、Peak W%pred、VO₂/kg@AT、Peak VO₂/kg、Peak VO₂/kg%pred、METs@AT、Peak METs、Peak METs%pred、O₂-pulse@AT、Peak O₂-pulse、Peak O₂-pulse%pred、VE/VCO₂slope、ΔVO₂/ΔWR、SBP@AT、Peak SBP、Peak DBP、HR@AT、Peak HR、Peak HR%pred and HRmax-HR1min of patients in the rehabilitation group before and after 6 months and the D-value of the corresponding indicators in the control group,there is statistical value（P<0.05）.4.The PHQ-9 and GAD-7 scores of patients in the rehabilitation group decreasing before and after 6 months,the difference exists certain statistical value（P<0.05）,while the discrepancy of the control group before and after 6 months has no statistical value（P>0.05）.A statistically significant difference between the D-values of PHQ-9 and GAD-7 scores before and after 6 months in the rehabilitation group was observed,compared to the control group’s scores（P<0.05）.5.The basic data and clinical characteristics of the patients in the rehabilitation group and the control group were analyzed by univariate analysis,and the variables of P<0.05 were screened from the univariate analysis,and the analysis results of the multivariate logistic regression equation were included.The D-value between Peak W%pred and Peak VO₂/kg%pred was found to be higher,and the more negative the D-value between GLU,Peak W,Peak DBP and PHQ-9 scores,the more likely it was that the rehabilitation group would receive sports rehabilitation treatment.Conclusion:1.Exercise rehabilitation therapy can strengthen cardiac and pneumonic functions of patients after PCI and delay the development of CHD.2.The anxiety and depression of patients after PCI can be improved by exercise rehabilitation therapy.