Exploration Of Clinical Application Value Of CMR Parameter Quantitative Technique In Myocardial Infarction

Objective: To investigate the clinical application value of quantitative technique of cardiac magnetic resonance parameters in diagnosing patients with myocardial infarction.Methods: 23 patients clinically diagnosed with myocardial infarction were enrolled in the infarction group,and 29 healthy volunteers were included in the control group.A 3.0T cardiac magnetic resonance instrument was used,and the scanning sequences included film sequences,T2 WI sequences,delayed enhancement,T1 and T2 mapping before enhancement and T1 mapping after enhancement.The left ventricular cardiac function parameters were analysed by CVI42 post-processing software.Then,the region of interest was achieved by delayed scanning,and T1 and T2 values of the region of interest were delineated,and extracellular volume fraction(ECV)was calculated by bringing in hematocrit.The above data were statistically analyzed and the difference between the two groups was comparable.P<0.05 was statistically significant.Results: The average age of the infarction group was(52.13±7.58)years old and that of the control group was(50.00±12.85)years older,the difference was not statistically significant(P > 0.05).The end diastolic volume(EDV),end systolic volume(ESV)and ejection fraction(EF)of infarct group were decreased compared with control group,and the difference was statistically significant(P < 0.001).There was no significant differences in stroke volume(SV)and cardiac output(CO)between the infarct group and the control group(P >0.05).In addition,the initial T1(1265.91±60.86)ms,T2(69.69±12.71)ms,ECV(35.16±2.59)% of the infarct group were higher than the initial T1(1071.75±43.77)ms,T2(52.06±5.93)ms of the healthy volunteers.ECV(30.39±3.18)% increased,and the difference was statistically significant(P<0.05).T1(439.82±24.86)ms in infarct group was less than that in control group(505.82±62.069)ms,and the difference was statistically significant(P<0.05).The infarct area was determined by delayed enhancement,and the diagnostic value of initial T1 was the highest(AUC=0.939)by ROC analysis of quantifiable parameters.Conclusion: Parameter quantitative technique can accurately diagnose infarction area and quantify its parameters,providing imaging data for early and accurate diagnosis of myocardial infarction.