Analysis Of CT Signs And Pathological Classification And EGFR Gene Mutation Correlation Analysis Of GGN’s Pulmonary Adenocarcinoma

Objective:(1)Discuss the correlation between CT signs and pathological classification that manifests as GGN.(2)Explore the correlation between the CT signs of influential pulmonary adenocarcinoma and the EGFR gene mutation of GGN.Methods:(1)Looking back at 144 CTs appeared as GGN,the pathological results were Adenocarcinoma in situ(AIS),Minimally invasive adenocarcinoma(MIA),and Invasive adenocarcinoma(IAC)CT signs and pathological materials.The patient’s age,average diameter,average density,the maximum diameter of the actual part,the density of the actual part of the actual part,and the pathological classification of the pathological category uses the rank and test;The dental signs,lymph node enlargement,distant metastases and pathological classification are compared with deck tests.(2)Looking back on sexual analysis 58 cases of Cancer Hospital Affiliated to the New Medical University,the pathological results are CT signs and genetic testing data of IAC.The CT signs are consistent with the first part of the study.Gene sequencing is divided into EGFR EXON-21 exogenous appendes L858 R mutations(later referred to as 21 exogenous sub-mutations),EGFR EXON-19 outer show 19-DEL mutation(later referred to as 19 exogenous sub-mutations)or EGFR wild group.Statistical methods are consistent with the first part of the study.Results:(1)Between the AIS,Mia,and IAC of GGN,there is no statistically significant significance of gender distribution,lymph nodes,and differences in distant metastasis(P> 0.05);The differences in the maximum diameter,solid density,and the remaining signs of the remaining CT are statistically significant(P<0.05).(2)The average diameter diameter of the lesions of the IAC EGFR gene mutation group,which is manifested as GGN,has a significant diameter diameter and real part of the solid part,which is significantly greater than the wild group,which is statistically significant(P <0.05).21 The average diameter and real diameter of the exogenous gene mutation group is greater than 19 exogenous sub-mutation groups,which is statistically significant(P<0.05).The rest of the general information and CT image data are not statistically significant(P> 0.05).Conclusion:(1)For lung adenocarcinoma presenting with GGN,the mean diameter,mean density,maximum diameter of solid part,density of solid part,smoking history,burr sign,lobulation sign,vacuolation sign,vascular fasciculation sign and pleural indentation sign of the lesion have important reference basis for the evaluation of lesion infiltration,and the mean diameter,mean density,density of solid part,maximum diameter of solid part and age have the highest evaluation value.Among them,the evaluation value of age factor is currently controversial in domestic and foreign studies.(2)Among the IACs presenting with GGN,the mean diameter of the lesion,the largest diameter of the solid part and the density of the solid part in the EGFR wild-type group were smaller than those in the EGFR gene mutation group,and the mean diameter and the diameter of the solid part in the exon 19 mutation group were smaller than those in the exon 21 mutation group.The combination of the largest diameter of the solid part of the lesion and the average diameter of the lesion had good reference value for the diagnosis of EGFR gene mutation and exon21 gene mutation.