Study On The Difference Between TCM Syndrome Distribution And Related Indexes Of Primary And Secondary Thrombocytopenia

Objective: To explore the distribution of TCM syndromes of primary immune thrombocyt openia(pITP)and secondary immune thrombocytopenia(sITP)and the relationship bet ween different syndromes and related indexes,and to explore the differences of the same i ndexes between the two diseases,so as to provide objective evaluation indexes and eviden ce-based basis for TCM syndrome differentiation and differential diagnosis.Methods:46 pITP patients and 32 sITP patients who met the inclusion and exclusion criteria were enroll ed.The four diagnostic information of these patients after diagnosis was collected.Accord ing to the diagnostic criteria of TCM syndromes,they were divided into yin deficiency an d internal heat syndrome,To explore the distribution characteristics and laws of four com mon TCM syndromes of yin deficiency and internal heat syndrome,qi failing to control bl ood syndrome,blood stasis syndrome and blood heat syndrome;The blood routine,five i tems of thyroid function,antinuclear antibody spectrum and bone marrow related indexes of patients who met the inclusion criteria were collected,and the relationship between diff erent syndromes and related indexes of pITP and sITP and the difference of the same inde xes between the two were analyzed.Results:1.Both pITP and sITP can occur in different a ge groups,with the highest frequency between 41 and 60 years old.In terms of gender rati o,women are more than men.2.Both pITP and sITP patients are mainly qi failing to contro l blood.3.In pITP patients,the mean PLT value of yin deficiency and internal heat syndro me was the highest.In sITP patients,the mean PLT value of qi failing to control blood syn drome was the highest.There was a statistically significant difference in MPV between T CM syndromes(P=0.043<0.05).4.In the comparison of platelet parameters between pITP and sITP,the difference of PDW was statistically significant(t = 4.184,P = 0.001 < 0.005).5.There were significant differences in total T3,total T4 and TSH between pITP and s IT P(P < 0.005).6.There was significant difference in the total number of megakaryocytes b etween pITP and sITP(P< 0.005).Conclusion:1.The distribution of TCM syndromes of p I TP and sITP has certain regularity,and the platelet parameter MPV can provide an objecti ve reference for the TCM syndrome differentiation of ITP.2.Platelet parameters,five items of thyroid function,antinuclear antibody spectrum related indicators and bone marrow im aging have certain reference value for the identification of pITP and sITP.