Study Of T2 Mapping On Knee Cartilage Injury In Patients With Diabetes

ObjectiveTo evaluate the clinical application value of MRI T2 mapping in knee cartilage injury in diabetic patients by measuring and analyzing the T2 values in different areas of knee cartilage in diabetic patients and healthy volunteers.Methods33 diabetic patients were selected as the case group,including 16 males and 17 females,ranging in age from 53 to 73 years old,with an average age of(62.42±5.820)years;30 healthy volunteers in the corresponding time period were recruited as controls group,including 14 males and 16 females,with an age range of 51 to 71 years,with an average age of(61.43±5.117)years.The MAGNETOM Amira free breathing 1.5T magnetic resonance scanner from Siemens,Germany,and the special coil for knee joint were used to scan the routine sequence(sagittal lipo-pressure PDWI sequence,sagittal T1 WI sequence,coronal lipopressing PDWI sequence,axial lipo-pressing PDWI sequence)and special sequence(sagittal T2 mapping sequence)of the knee joint of all subjects.After scanning,all imaging data were transferred to Siemens’ own workstation for processing,The T2 mapping pseudo-color image is automatically generated.Select the appropriate region of interest(ROI),and measure the T2 value of the medial femoral condyle,lateral femoral condyle,medial tibial plateau,lateral tibial plateau and patella cartilage in the case group and the control group respectively.Input its imaging data into the workstation,and use Microsoft Office Excel 2019 and IBM’s SPSS25.0 statistical software to enter,process and statistically analyze the collected data.Results1.The case group consisted of 16 males and 17 females,aged 53-73 years,with an average age of(62.42±5.820)years old,with 19 left knees and 14 right knees;the control group consisted of 14 males and 16 females,aged 51-71 years,with an average age of(61.43±5.117)years,the distribution of knee joints was 19 cases in the left knee and 14 cases in the right knee.The P values of gender,age and knee joint distribution between the diabetic patients and the healthy volunteers were above 0.05,and the differences were not statistically significant.2.The average T2 values of cartilage in five ROI areas(medial and lateral condyles of femur,medial and lateral plateaus of tibia and patella)in the case group and the control group are respectively(42.78±5.07,36.06±4.81)ms,(44.34±4.39,37.60±4.86)ms,(38.66±5.55,34.11±4.07)ms,(40.43±4.65,33.44±4.53)ms,(30.76±3.60,25.20±3.50)ms.The average T2 value of cartilage in five ROI areas in the case group was higher than that in the control group,and the difference was statistically significant(P<0.001).3.The mean T2 values of cartilage in different areas of the case group were not all the same,and the difference was statistically significant(F=41.866,P=0.000).4.The average T2 value of cartilage in different areas of the case group was compared with each other,and the differences among medial and lateral condylar cartilage of femur,medial and lateral plateau cartilage of tibia and patella cartilage were statistically significant(P<0.05).There was no significant difference between medial femoral condyle cartilage and lateral femoral condyle cartilage(P=0.177),and between medial tibial plateau cartilage and lateral tibial plateau cartilage(P=0.128).ConclusionT2 mapping imaging technology provides quantitative indicators for evaluating the degree of knee cartilage injury in diabetic patients,and provides image basis for diagnosis and monitoring of knee cartilage injury in diabetic patients,which has certain clinical value.