Clinical Observation On The Treatment Of Pharyngitis Caused By Spleen Deficiency With Jianpi Liqi Decoction Based On The Theory Of "dry Throat Disease In Spleen Soil"

Objective: According to the theory of "dry throat disease in spleen soil" in the classical ancient books of traditional Chinese medicine Suwen Yin and Yang Theory,combined with the concept of holism in traditional Chinese medicine and the principle of treatment based on syndrome differentiation,this article observed patients who took self-made Jianpi Liqi Decoction in the treatment of chronic pharyngitis with spleen deficiency syndrome,and objectively evaluated the clinical efficacy improvement of Jianpi Liqi Decoction in the treatment.It provides ideas for developing more and more effective Chinese medicine preparations for the clinical treatment of chronic pharyngitis with spleen deficiency syndrome.Methods: This monitoring process was for eighty patients with chronic pharyngitis and spleen deficiency syndrome form the Department of Otolaryngology,Affiliated Hospital of Changchun University of Chinese Medicine.The subjects were randomly divided into two groups: treatment team and comparison team,forty patients in each team.The treatment team was treated with Jianpai Liqi Decoction,and the comparison team was treated with Buzhong Yiqi Decoction.Seven days was considered as a course of treatment,and the medication was continued for two courses of observation.At the time of initial diagnosis,7days after treatment and 14 days after treatment,the patients in the two groups were recorded in the form of clinical observation tables,and the therapeutic effects of major symptoms,minor symptoms and signs before and after treatment in the two groups were studied by statistical analysis.If there are any adverse reactions,they should also be recorded.Results: 1.This study finally included 76 patients,39 cases in the treatment group and37 cases in the control group.There was no significant difference in age,sex,course of disease and various observation indexes before treatment between the two groups(P>0.05),which was comparable.2.Comparison of main symptoms: After 7 days of treatment,there were statistical differences in the improvement of foreign body sensation or phlegm adhesion,dry throat and sore throat between the two groups(P<0.05),but there were no statistical differences in the improvement of itchy throat,cough and hiccup(P>0.05);After 14 days of treatment,the symptoms of foreign body sensation or phlegm adhesion,dry throat and sore throat,hiccup and acid regurgitation in the two groups were statistically significant(P<0.05),but there was no statistical significance in improving itchy throat and cough(P>0.05).3.Comparison of signs: After 7 days of treatment,there was a statistical difference between the two groups in improving congestion of pharyngeal mucosa(P<0.05),but there was no statistical difference in reducing lymphofollicular hyperplasia of posterior pharyngeal wall(P>0.05);After 14 days of treatment,there were significant differences between the two groups in improving pharyngeal mucosal congestion and lymphofollicular hyperplasia(P<0.05).4.Comparison of secondary symptoms: After 7 days of treatment,there was no statistical significance in improving the symptoms of bloating,nausea,loose stool anorexia and fatigue in the two groups(P>0.05);After 14 days of treatment,the symptoms of bloating,nausea and loose stool’s anorexia in the two groups were statistically different(P<0.05),but there was no statistical significance in improving the symptoms of burnout and fatigue(P>0.05).5.Comparison of total effective rate: After 7 days of treatment,the total effective rate in the treatment group was 71.79%,and that in the control group was 45.95%,with statistical analysis(P=0.023);After 14 days of treatment,the total effective rate was94.87% in the treatment group and 81.08% in the control group,with statistical analysis(P=0.000).There was a significant difference between the two courses of treatment(P<0.05).Conclusion: Through the study,the two teams can treat the chronic pharyngitis effectively.Jianpi Liqi Decoction has a significant effect on the treatment of chronic pharyngitis with spleen deficiency syndrome,and can significantly improve the symptoms and signs of patients.These results indicated that the spleen was reliable for the treatment of pharynx based on the theory of "dry throat disease in spleen soil".There was no adverse reaction in the treatment process,indicating that Jianpi Liqi Decoction was safe for the treatment of chronic pharyngitis with spleen deficiency syndrome.