| Osteoporosis（OP）is the most common bone disease.It is a systemic bone disease characterized by low bone mass,microstructural damage of bone tissue,increased bone fr-agility and prone to fracture[1].In 2001,the National Institutes of Health（NIH）defined it as a bone disease characterized by decreased bone strength and increased fracture risk,suggesting that bone loss is a major risk factor for osteoporotic fractures,but There are other risk factors[2].Once patients have osteoporosis,their bone mass will begin to decrease gradually,and their bones will gradually increase in brittleness,resulting in lower body height,hunchback,decrea-sed muscle strength and back pain,which will have a serious impact on patients’quality of lif-e.Osteoporosis has become a global public health problem,and its fragile fractures can cause disability and seriously affect the quality of life of patients.A series of complications often oc-cur after fracture,such as long-term bed rest after fracture,often venous thrombosis of the lower extremity,hypostatic pneumonia,hemorrhoids,etc.,severe pulmonary embolism may even endanger the life of the patient,such as hip fracture in the elderly,incidence Extremely high,it is the last fracture in life.With the improvement of people’s living standards and the pursuit of health,osteoporosis has gradually attracted everyone’s attention.How to prevent os-teoporosis and osteoporotic fractures is called the current hot topic.The Chinese medicine of this disease is classified as the"bone callus"category.Chinese medicine believes that osteoporosis is a natural manifestation of human aging.For example,in the"Nei Jing":"The woman is 42 years old...;the man is 48...".But if you age too quickly,the corresponding symptoms will appear and need treatment.Chinese medicine believes that the kidney is the innate foundation,The treatment of osteoporosis starts with tonifying liver and kidney.Commonly used proprietary Chinese medicines such as Jintiange capsules,Jianbu Hu Qian pills,etc.;Chinese medicine believes that the spleen is the mother of nurture,source of Qi and Blood.There are also some signs of spleen deficiency in osteoporosis.On the basis of the classical medical theory of the motherland,we summed up the experience in long-term clinical practice and found that there are many patients with osteoporosis in the spleen-defici-ency type in the clinic,or some patients with liver and kidney deficiency also have spleen deficiency.This research is based on this evidence.This study mainly explores the clinical efficacy of strengthen spleen therapy in these populations.Objective:To explore the clinical effect of strengthen spleen therapy in the treatment of osteoporotic pain of spleen-deficiency type,and to compare the curative effect of traditional Chinese medicine Jintiange capsule,to explore the advantages of traditional Chinese medicine in treating osteoporosis pain,and to provide a clinical basis for the treatment of osteoporosis from the spleen and stomach.Methods:Sixty patients with osteoporosis diagnosed from December 2017 to November2018 in the The Third Affiliated Hospital of Beijing University of Chinese Medicine Hospital were randomly divided into experimental group and control group,with 30 cases in each gro-up.The experimental group was treated with strengthen spleen Recipe,and the control group was treated with Jintiange Capsule for 12 weeks.The body examination was performed before and 12 weeks after the treatment,including the clinical symptom score and visual analog pain score（VAS）of patients with osteoporosis.Bone mineral density（BMD）,blood calcium,blood phosphorus,alkaline phosphatase,liver and kidney function,electrocardiogram,etc.,while recording treatment efficiency and adverse drug reactions.Screen valuable indicato-rs to assess efficacy.Results:（1）After 12 weeks of treatment,the clinical symptoms and pain of the experiment-al group and the control group were significantly improved（P<0.05）.In the improvement of clinical symptoms and pain,the experimental group was superior to the control group（P<0.05）;In the improvement of bone mineral density,the improvement of the experimental group and the control group were not obvious（P>0.05）.（2）The effective rates of the experimental group and the control group were 77.78%and 37.04%,respectively,and the experimental group was significantly better than the control group（P<0.05）.Conclusion:The spleen strengthening therapy has significant clinical effect on patients with osteoporotic pain of spleen deficiency type. |
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