Research On Therapeutic System Based On Electrical Stimulation Technology And IMU Acquisition Technology And Its Application In PFD

Pelvic floor dysfunction(PFD)is a common disease that plagues women.Nearly one quarter of adult women suffer from PFD.With the full liberalization of the two child and three child policies,the incidence rate of PFD also increases.At present,the widely used PFD treatment methods include passive electrical stimulation and active pelvic floor muscle training(PFMT).Passive electrical stimulation therapy uses electrodes to stimulate the pelvic floor muscles to improve muscle activity.Active PFMT means that patients can improve muscle strength and coordination by actively contracting the pelvic floor muscles.However,the current electric stimulation treatment uses dual channel hard electrodes to stimulate the entire pelvic floor muscle.The treatment method is generally solidified,and it is unable to provide accurate electric stimulation for different damaged muscle parts and muscle states of individuals;The existing feedback of PFMT depends on the EMG waveform and parameters of the whole muscle,which cannot provide effective and accurate displacement of muscles in each region during pelvic floor contraction.Therefore,it is of great significance for clinical treatment of PFD to develop an accurate and personalized PFD treatment system to break through the limitations of fuzziness and templating in traditional schemes.In this study,a multi-channel pelvic floor electrical stimulation system based on electrical stimulation(ES)and a pelvic floor motion feedback system based on inertial measurement unit(IMU)were designed to solve the above problems.It can realize multi-site precise electrical stimulation treatment of pelvic floor muscle and PFMT scheme based on pelvic floor motion track feedback.The main work and innovations of the paper are as follows:(1)A multi-channel pelvic floor electrical stimulation system has been designed and developed,including four output channels.It is equipped with a site selection module,which can connect multi-site pelvic floor airbag electrodes customized according to the distribution of pelvic floor muscles.The system can output symmetrical bipolar rectangular wave with constant current,and the stimulation parameters can be adjusted through the GUI on the PC.The adjustment range of stimulation intensity is 0-100m A,the adjustment range of stimulation frequency is 0-200Hz,and the adjustment range of stimulation pulse width is 50-600μs.The maximum output support load is 1.5kΩ.Through the test,the error of stimulus intensity and frequency is within 8%and 1%respectively,and the error of stimulus pulse width is within 5%.(2)Based on multi-channel electrical stimulation system,animal experiments and clinical experiments were carried out.Animal experiments were conducted to investigate the effects of electrical stimulation parameters on the efficacy of different pelvic floor muscles in SUI rats.The experimental results showed that 60Hz frequency was better for the treatment of urethral sphincter injury,and 30Hz frequency was better for the treatment of anal external sphincter injury.The clinical experiment explored the effect of multi-site design on SUI patients.The experimental results show that the design of multi-site electrical stimulation can specifically stimulate the regional muscles.The muscle strength in the stimulated area and outside the area has been significantly improved,and the frequency of urine leakage of patients has been significantly reduced.The safety,stability and effectiveness of multi-channel pelvic floor electrical stimulation system were verified through experiments.(3)A pelvic floor motion trajectory feedback system is designed and developed.The system uses a flexible vaginal probe containing an IMU module to obtain pelvic floor motion data,including three-axis acceleration,three-axis angular velocity and three attitude angles.The data is uploaded to the PC for analysis and drawing,and the motion trajectory is displayed on the GUI interface in real time to guide patients to perform PFMT.The system power consumption is only 2.5m W,and the size of flexible sensor array is 3×1×40mm~3,which will not hinder the deformation of the basin bottom.Through measurement,the angular velocity zero drift error and sampling error are within 2dps and 2%respectively,and the acceleration zero drift error and sampling error are 0.1g and 2%respectively.