| Objective: To evaluate the application value of six-minute walk test in patients with chronic heart failure by studying the correlation between six-minute walk test and BNP,LVEF,LVDd and cardiac function grading indexes of NYHA in patients with chronic heart failure and comparing the changes of six-minute walk distance before and after the use of ’ new quadruple ’ therapy.Methods: From January 2021 to June 2022,fifty patients suffering from chronic heart failure were hospitalized at the First Affiliated Hospital of Kunming Medical University..The researchers all took standardized heart failure drug treatment,that is,the use of ’ new quadruple ’ therapy,that is,ACEI/ARB/ARNI +β-blockers+MRA +SGLT2 inhibitors composed of ’ new quadruple ’ program for three months of clinical observation.Of the 29 males and 21 females,aged 68.72 ± 5.63 years,26 had coronary heart disease,4 had dilated cardiomyopathy,20 had high heart disease,and the course of disease was 6.08 ± 2.08 years.Additionally,2 had cardiac function grade I,9 had cardiac function grade II,26 had cardiac function grade III,and 13 had cardiac function grade IV.The clinical application value of 6MWT for CHF was evaluated by analyzing the correlation between 6MWT and BNP,LVEF,LVDd and cardiac function grading indexes before treatment and comparing 6MWD with BNP,LVEF,LVDd and cardiac function grading indexes after three months.Results:1.After three months of ’new quadruple’ therapy,BNP and LVDd decreased,6MWD and LVEF increased,with a statistically significant difference(P <0.05).2.After linear correlation analysis,6MWD was significantly negatively correlated with BNP(r =-0.817,P < 0.01),6MWD was significantly positively correlated with LVEF(r = 0.894,P < 0.01),6MWD was significantly negatively correlated with LVDd(r =-0.694,P < 0.01),6MWD was significantly negatively correlated with NYHA cardiac function classification(r =-0.758,P < 0.01).Conclusions: 1.There is a correlation between 6MWT and BNP,LVEF,LVDd and NYHA cardiac function classification in CHF patients,which can be used as one of the daily monitoring methods for cardiac function examination in CHF patients.2.The six-minute walking distance of patients receiving ’ new quadruple ’treatment increased,suggesting that the six-minute walking test can guide and evaluate the efficacy of CHF patients.3.The 6MWT not only has good safety,but also can simultaneously evaluate the activity tolerance and cardiopulmonary function of CHF patients,which is worthy of clinical application. |