| Objective: To compare and study the academic characteristics and medication rules of Ye’s Gynecology Syndrome and Treatment and Fu’s Gynecology.Methods:1.Construct the "Diseases–Symptoms–Syndrome Elements–Prescriptions–Traditional Chinese Medicines" database of Ye’s Gynecology Syndrome and Treatment and Fu’s Gynecology.2.Data analysis and data mining,including frequency statistics,web analysis,clustering models,association rules and decision trees.3.By comparing the data analysis and mining results of the two books,summarize and compare the academic characteristics and medication rules of the two books.Results: 1.The author of Fu’s Gynecology is indeed Fu Shan,but his medical skills may have been passed down from Taoist masters,and Ye’s Gynecology Syndrome and Treatment should have been written by a monk,under the name Ye Gui.2.The number of diseases contained in Ye’s Gynecology Syndrome and Treatment is significantly more than that in Fu’s Gynecology.It discusses various types of diseases,but the exposition of a single disease is relatively concise.On the other hand,Fu’s Gynecology is relatively precise and detailed.It selects fewer types of diseases.Most of the diseases it discusses are selected common diseases,and the content is more detailed,including symptoms,causes,pathogenesis and prescriptions.All are fully prepared.3.There are significantly more prescriptions in Ye’s Gynecology Syndrome and Treatment than in Fu’s Gynecology.Most of each disease has more than one prescription,even as many as ten or more,while Fu’s Gynecology is mostly one prescription of one disease.4.There are few original prescriptions in Ye’s Gynecology Syndrome and Treatment,and the excerpted prescriptions are mostly from "Jingyue Quanshu","Taiping Huimin Heji Jufang" and "Shengji Zonglu";Fu’s Gynecology are mostly original prescriptions.5.Ye’s Gynecology Syndrome and Treatment uses more dosage forms.In addition to decoction,it also uses more pills,powders,wine and ointment,while Fu’s Gynecology has only one pill except for decoction..6.Ye’s Gynecology Syndrome and Treatment has many requirements for decoction media.In addition to water decoction,there are also wine decoction,river decoction,half decoction in vinegar water and so on,while Fu’s Gynecology has only one prescription of decoction in river water except for decoction in water.7.Ye’s Gynecology Syndrome and Treatment has a variety of pill preparation methods.In addition to honey pills,there are rice paste pills,vinegar paste pills,water pills and so on,while Fu’s Gynecology has only one pill of honey pills.8.Ye’s Gynecology Syndrome and Treatment has higher requirements on the time of taking medicine,such as hollow,after-meal,pre-meal and so on,while Fu’s Gynecology has no relevant description.9.Ye’s Gynecology Syndrome and Treatment uses many different guides of decoction.In addition to common guides such as ginger,green onion,and jujube,there are also guides such as glutinous rice,rushes,plums and so on,while Fu’s Gynecology has a lotus leaf as a guide of decoction.10.Ye’s Gynecology Syndrome and Treatment has higher requirements on the delivery medium of pills and powders such as white soup,wine,rice drink and so on,while Fu’s Gynecology has no relevant description.11.There is often a description of the number of medicines about the prescription in Fu’s Gynecology,but there is no relevant description in Ye’s Gynecology Syndrome and Treatment.12.The average number of flavors per prescription in Ye’s Gynecology Syndrome and Treatment is slightly less than that in Fu’s Gynecology,but the dosage of some pills is often higher.13.The proportion of blood-tonifying drugs is higher in Ye’s Gynecology Syndrome and Treatment,while the proportion of qi-invigorating drugs in Fu’s Gynecology is higher.14.The traditional Chinese medicines used in Ye’s Gynecology Syndrome and Treatment but not in Fu’s Gynecology include Muxiang,Qingpi,Alisma,Angelica and so on,which are used in Fu’s Gynecology but not in Ye’s Gynecology Syndrome and Treatment The traditional Chinese medicines are Morinda officinalis,North American ginseng,Yinchen and so on.15.The disease site of Ye’s Gynecology Syndrome and Treatment is mainly in the spleen and stomach,while the disease site of Fu’s Gynecology is mainly in the liver and kidney,taking into account the spleen and stomach.16.In the chapter on menstruation regulation,Ye’s Gynecology Syndrome and Treatment has more blood and qi,while Fu’s Gynecology strengthens the spleen more.In the Qiuzi chapter Ye’s Gynecology Syndrome and Treatment has more blood tonic,while Fu’s Gynecology has more warm and invigorate kidney yang.17.In the chapter on menstruation regulation,the disease site of Ye’s Gynecology Syndrome and Treatment is mainly in the spleen,while the disease site of Fu’s Gynecology is mainly in the liver and kidney.In the abortion chapter,the disease site of Ye’s Gynecology Syndrome and Treatment is mainly located in The spleen and stomach,and the disease location of Fu’s Gynecology is mainly in the kidney.In the section on preservation of labor,the cause of Ye’s Gynecology Syndrome and Treatment is mainly exogenous pathogens,while the cause of Fu’s Gynecology is mainly internal injury.18.In the menstrual adjustment chapter,Ye’s Gynecology Syndrome and Treatment contains more spleen and stomach symptoms of loss of appetite,while Fu’s Gynecology does not;The following blood is the main symptoms of Fu’s Gynecology.19.The maximum and common doses of commonly used traditional Chinese medicines in decoction in Fu’s Gynecology were significantly higher than those in Ye’s Gynecology Syndrome and Treatment.20.The two books Ye’s Gynecology Syndrome and Treatment and Fu’s Gynecology both attach importance to the description of the processing method,and most traditional Chinese medicines have recorded their processing methods.21.The combination with the highest number of links in the traditional Chinese medicine web analysis of Ye’s Gynecology Syndrome and Treatment is Angelica –Chuanxiong,while the combination with the highest number of links in the traditional Chinese medicine web analysis of Fu’s Gynecology is Atractylodes – Ginseng.22.The combination with the highest number of links in the symptom web analysis of Ye’s Gynecology Syndrome and Treatment is loss of appetite – fatigue,while the combination with the highest number of links in the symptom web analysis of Fu’s Gynecology is dizziness – dizziness.23.In the clustering analysis of traditional Chinese medicines in Ye’s Gynecology Syndrome and Treatment,the drug groups with a distance less than 5 are Angelica –Chuanxiong,while in the clustering analysis of traditional Chinese medicines in Fu’s Gynecology,the drug groups with a distance less than 5 are Atractylodes – Ginseng and Rehmannia glutinosa – Cornus.24.In the clustering analysis of symptoms in Ye’s Gynecology Syndrome and Treatment,the combinations with a distance less than 5 are fetal restlessness – pregnancy confidant fullness and loss of appetite – fatigue,while in the clustering analysis of symptoms in Fu’s Gynecology,the distance is less than 5 The combination is dizziness– dizziness.25.The two-combination medicine group shared by the two books Ye’s Gynecology Syndrome and Treatment and Fu’s Gynecology is Angelica – Astragalus,Rehmannia glutinosa – Cornus,Angelica – Chuanxiong and Ginseng – Astragalus,and the triple medicine group is Ginseng – Astragalus – Atractylodes,the common quadruple medicine group is Ginseng – Astragalus – Atractylodes – Angelica.26.The two books Ye’s Gynecology Syndrome and Treatment and Fu’s Gynecology share the common rule of medication based on syndrome elements as Qi deficiency –spleen → Atractylodes and spleen → Atractylodes,and the common rule of medication based on symptoms is Irritability → Paeonia lactiflora.27.The decision tree rules shared by the two books Ye’s Gynecology Syndrome and Treatment and Fu’s Gynecology are: if Astragalus = T,then Angelica = T;if Paeonia lactiflora = T,then Angelica = T;if Cornus = T,then Rehmannia glutinosa = T;if Cornus= F and Paeonia lactiflora = F,then Rehmannia glutinosa = F.Conclusion: Through the research of this topic,the academic characteristics and medication rules of Ye’s Gynecology Syndrome and Treatment and Fu’s Gynecology have been obtained,and the standard process of data mining technology to study ancient Chinese medicine books has been formed,providing ideas and references for the study of other Chinese medicine works.The research of this topic provides data support for the construction of the theoretical system of traditional Chinese medicine,and lays a foundation for further deep learning and the construction of an intelligent diagnosis and treatment system of traditional Chinese medicine. |