| Research 1:A study on the correlation between allergic rhinitis and adenoid hypertrophyObjective:To analyze whether the presence of adenoid hypertrophy(AH)affects the duration and severity of allergic rhinitis(AR),as well as the correlation between adenoid hypertrophy and common symptoms of allergic rhinitis,and to explore the correlation between the duration and severity of allergic rhinitis and the size of adenoids.Method:According to the presence or absence of adenoid hypertrophy,the children were divided into two groups:simple AR group and AR+AH group,including 25 cases of simple AR group and 17 cases of AR+AH group.At the same time,for children with AR combined with AH group,children with adenoid hypertrophy were divided into mild obstructive group and severe obstructive group based on the degree of adenoid hypertrophy.Compare the condition of children with the simple AR group and the AR combined with AH group,analyze the differences in symptom duration and severity,and observe the correlation between adenoid hypertrophy and common symptoms of allergic rhinitis,in order to analyze the impact of adenoid hypertrophy factors on the condition of children with allergic rhinitis.Compare the correlation between children with adenoid hypertrophy of different sizes and the duration and severity of allergic rhinitis in the group of AR with AH.Result:A total of 42 children who met the inclusion criteria were included in this study.Among them,17 children were diagnosed with adenoid hypertrophy after nasopharyngoscopy examination showed that more than 50%of the posterior nostrils were blocked by adenoids,and the proportion of AH in AR was 40.48%.The proportion of children with adenoid hypertrophy in the Preschool age was 66.7%,and the proportion of children with adenoid hypertrophy in the school age was 25.9%.There was a statistically significant difference in age groups between the two groups(P=0.035<0.05).In the simple AR group,the proportion of children with persistent rhinitis was 32.0%,and in the AR combined with AH group,the proportion of children with persistent rhinitis was 64.7%.The incidence of persistent rhinitis was higher in the AR combined with AH group,and the difference was statistically significant(P=0.037<0.05).Children with moderate to severe rhinitis accounted for 36.0%in the simple AR group,and 70.6%in the AR combined with AH group.The incidence of moderate to severe rhinitis was higher in the AR combined with AH group,and the difference was statistically significant(P=0.028<0.05).We found that the incidence of nasal congestion was 100.0%in the AR combined with AH group,while 80.0%in the simple AR group.The incidence of nasal congestion in the AR combined with AH group was higher than that in the simple AR group(P=0.049<0.05).Meanwhile,the incidence of nasal itching in children with simple AR was 96.0%,while 70.6%in the AR combined with AH group.The incidence of nasal itching in children with simple AR was higher than that in children with AR combined with AH(P=0.021<0.05).There was no statistically significant difference in sneezing and runny nose between the two groups.Conclusion:In this study,the incidence rate of adenoidal hypertrophy in allergic rhinitis is 40.48%.Combined with other clinical studies,it shows that the incidence of adenoidal hypertrophy in children with allergic rhinitis is high.AR is a risk factor for AH,so there is a certain association between them.The incidence of adenoid hypertrophy in children with allergic rhinitis in preschool age is higher than that in school age,which is consistent with our current understanding that adenoids proliferate vigorously at the age of 2 to 6 and begin to atrophy at the age of 10.For the comparison of the severity and duration of allergic rhinitis between two groups,it can be found that for AR children with AH,the severity of allergic rhinitis is heavier and the duration is longer than that without AH,indicating a certain positive correlation between AR and AH.For the comparison of allergic symptoms of rhinitis between two groups,the incidence of nasal congestion in the AR combined with AH group was higher than that in the simple AR group,while the incidence of nasal itching was lower than that in the simple AR group.Research 2:Clinical Observation on the Therapeutic Effect of Fuzheng Tongqiao Formula on Allergic Rhinitis of Lung and Spleen Deficiency Type in ChildrenObjective:To objectively evaluate the clinical efficacy of "Fuzheng Tongqiao Formula" in the treatment of pediatric allergic rhinitis by evaluating and comparing the scale scores of symptoms.Method:Using a random number table method,children with lung spleen deficiency type allergic rhinitis who received outpatient treatment at Dongcheng Hospital and Tongzhou Hospital of Beijing University of Traditional Chinese Medicine from January 2022 to January 2023 were divided into two groups.All research subjects met the inclusion criteria but did not meet the exclusion criteria,including 25 in the experimental group and 24 in the control group.The treatment group was treated with Fuzheng Tongqiao Formula for 2 weeks,while the control group was treated with Monelukast Sodium for 2 weeks.Collect general case information of the patient before treatment,and record the patient’s main symptom and secondary symptom score scale before treatment,1 week after treatment,and 2 weeks after treatment.Result:1.Case inclusion status:A total of 49 children who met the inclusion criteria were included in the study,of which 25 were in the experimental group and 1 was excluded.There were 24 cases in the control group,with 1 case excluded and 1 case lost.This study included a total of 46 effective cases(24 in the treatment group and 22 in the control group).2.General situation:Among the cases included in this study,there were slightly more boys than girls,with children aged 3-6 being the most common,followed by children aged 7-10,with children aged 4 being the most included.46%of the cases had a family history of allergic diseases,and most of the children had allergic diseases themselves,most of which were eczema,followed by allergic conjunctivitis.Food allergies and urticaria’ also account for a certain proportion.3.Clinical efficacy:The effective rate of the experimental group was 95.8%,and the recovery rate was 66.7%.The effective rate of the control group was 95.5%,and the recovery rate was 9.1%.The overall efficacy of the experimental group was better than that of the control group(P<0.05).The improvement of total symptom scores in the experimental group after 2 weeks of treatment was better than that in the control group(P<0.05).After one week of treatment,there was no significant statistical difference(P>0.05)between the experimental group and the control group in terms of the four main symptoms of nasal itching,runny nose,sneezing,and nasal congestion.After two weeks of treatment,the improvement of the scores of each main symptom in the experimental group was significantly better than that in the control group(P<0.05),except for nasal congestion.There was no significant statistical difference(P>0.05)in the improvement of nasal congestion between the two groups.For the improvement of secondary symptoms of allergic rhinitis caused by lung spleen deficiency syndrome,The experimental group was significantly better than the control group except for anorexia(P<0.05),and there was no significant statistical difference in improvement of anorexia between the two groups(P>0.05).Intragroup comparison:The experimental group and control group showed significant improvement in the scores of the four major symptoms after treatment(P<0.05).The experimental group showed improvement in all secondary symptoms after treatment compared to before treatment,while the control group showed no significant improvement in secondary symptoms except for anorexia(P>0.05).The control group also showed some improvement in anorexia(P<0.05).Conclusion:After 2 weeks of treatment,the therapeutic effect of the Fuzheng Tongqiao Formula group is better than that of the Monelukast Sodium group.Whether it is the improvement of the main symptom or the improvement of the secondary symptom,the Fuzheng Tongqiao Formula has a better therapeutic effect. |
