Clinical Observation On The Therapeutic Effect Of Modified Gongdi Decoction In The Treatment Of Female Stress Urinary Incontinence With Kidney Yang Deficiency Syndrom

Objective : To observe the efficacy and safety of Jiawei Gongdi Decoction in the treatment of female stress urinary incontinence with kidney yang deficiency syndrome.Methods : The patients were randomly divided into observation group and control group with 32 cases in each group.Observation group : On the basis of basic treatment,the traditional Chinese medicine Jiawei Gongdi Decoction was taken,and the traditional Chinese medicine was cooked and bagged,150 ml per bag,1 bag each time,twice a day,and the treatment was continued for 30 days.Control group : On the basis of basic treatment,oral administration of western medicine midodrine hydrochloride-adrenergic agonist(produced by Guantong Naikeming Co.,Ltd.)2.5mg / time,3 times / day,medication treatment period of 30 days.Basic treatment : The patient was guided by the medical staff to perform pelvic floor muscle training called Kegel exercise.Before treatment,the bladder should be emptied,a comfortable posture should be selected,and the hip and abdominal muscles should be relaxed.Shrink the abdominal and hip muscles for 8 seconds when inhaling and relax for 8 seconds when exhaling.So as to achieve the purpose of awakening muscles and strengthening contraction function.Practice once a day for 30 minutes each time for 30 days.Results : The observation group and the control group were statistically significant in symptom score,kidney yang deficiency symptom score,safety comparison,and abdominal pressure leak point pressure(VLPP)(P < 0.05).There was no significant difference in I-QOL score and ICI-Q-SF score between the two groups(P > 0.05).The total effective rate of improving TCM syndromes in the two groups was 81 % and 53 %respectively,and the difference was statistically significant(P<0.05).The effective rates of the two groups in the overall efficacy were 88 % and 69 %,respectively,and the difference was not statistically significant(P > 0.05).Conclusion : Both groups can treat female stress urinary incontinence patients with kidney-yang deficiency syndrome in traditional Chinese medicine,and the overall efficacy is comparable.However,Jiawei Gongdi Decoction can better improve the degree of symptoms and improve VLPP,and in improving TCM syndromes and TCM efficacy evaluation,Jiawei Gongdi Decoction has better efficacy.And there are few adverse reactions,higher safety.