Study On The Correlation Between TCM Syndrome Types And Objective Indicators Of Alcoholic Liver Cirrhosi

Objective: By collecting the general information and objective indicators of patients with alcoholic cirrhosis,this paper summarizes and analyzes the TCM syndromes of patients with alcoholic cirrhosis,comprehends the characteristics of TCM syndromes of alcoholic cirrhosis,and investigates the correlation between TCM clinical syndromes and objective indicators,so as to deeply study the diagnosis and treatment ideas of Professor Lu Bingjiu,and provide theoretical foundations for TCM syndrome differentiation and classification of alcoholic cirrhosis,consequences giving clinical scientific research ideas for TCM diagnosis and treatment of the disease.Methods: This study collected the patients who were treated in the hepatopathy clinic of the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine from 1September 2015 to 30 June 2022,screened the cases according to the inclusion and exclusion criteria,and made a retrospective analysis of 238 patients with alcoholic cirrhosis who met the criteria,collecting the basic information of the patients,including their gender,age,alcohol consumption,drinking years,etc.And objective indicators include alanine aminotransferase(ALT),aspartate aminotransferase(AST),gamma-glutamine transpeptidase(GGT),serum albumin(ALB),serum total bilirubin(TBIL),prothrombin time(PT),activated partial thromboplastin time(APTT),alpha-fetoprotein(AFP)and alkaline phosphatase(ALP).Then,according to the four clinical diagnosis information of patients,According to the 2011 Consensus on the Diagnosis and Treatment of Cirrhosis by Integrated Traditional Chinese and Western Medicine,the patients were divided into six syndromes: stagnation of liver-qi syndrome,internal resistance of water-dampness,accumulation of damp-heat,yin deficiency of liver and kidney,yang deficiency of spleen and kidney,and obstruction of collaterals by blood stasis.Statistical analysis was conducted by SPSS27.0 software to understand the distribution characteristics of TCM syndromes of alcoholic liver cirrhosis,and to explore the TCM syndromes of alcoholic liver cirrhosis,gender,age,drinking years and days.Results:1.A total of 238 patients with alcoholic cirrhosis were collected,with the gender distribution as follows: 230 males and 8 females.2.Distribution of six TCM syndromes: 48 patients of stagnation of liver-qi,64 patients of water-dampness accumulation,74 patients of damp-heat accumulation,20 patients of liver-kidney yin deficiency,14 patients of spleen-kidney yang deficiency and 18 patients of blood stasis blocking collaterals.3.Among the TCM syndrome types of 238 patients with alcoholic cirrhosis,74 cases(31.1%)have damp-heat accumulation syndrome,and 14 cases(5.9%)have spleen-kidney yang deficiency syndrome.4.Analysis of TCM syndrome types and general situation of 4.ALC patients,in which age,drinking years and average daily drinking amount are distributed differently among the six standardized syndrome types,with statistical significance.5.Correlation analysis between TCM syndromes of 5.ALC patients and objective indicators showed that the levels of ALT,AST,GGT,TBIL,ALB,PT,APTT and AFP were different in different TCM syndromes,with statistical significance.Among them,the ALB level of liver-qi stagnation syndrome is the highest,and the levels of TBIL,PT,APTT and ALP are the lowest.The values of ALT,AST,GGT,TBIL,PT and AFP in damp-heat accumulation syndrome ranked first;The values of ALT,GGT and ALB in liver and kidney yin deficiency syndrome are theminimum;AST and AFP values of spleen-kidney yang deficiency syndrome are the minimum;The values of APTT and ALP in blood stasis syndrome are the highest.Conclusion:1.The number of years of drinking and the amount of daily drinking have influence on the onset of alcoholic cirrhosis and the TCM syndrome types.2.Objective indicators(ALT,AST,GGT,ALB,TBIL,ALP,PT,APTT,AFP)have certain correlation with TCM syndromes of alcoholic cirrhosis.