Overview Of Asthenospermia Caused By Chronic Prostatitis Treated With Cleaning Heat And Nourishing Kidney Methods

Objective: Male infertility caused by Chronic Prostatitis (CP) is common seen in andrology. because infertility is caused by various reasons in both gender, therefore to treat the disease should engage in CP. CP is the most common seen disease in male reproductive system, it is likely to occur in the prime age between 20-40 years of age. There is likely not much symptom when CP happens, only feel a little occult pain in perineal region or deep part of urethra, frequent micturition or burning sensation, a few secretion after urinate, especially after drink or eating hot food or overwork, the symptom will manifest. Many scientists consider that abnormal of immune function in regional prostate gland is a radical reason result in bad recovery or recur, that causes in short of effective methods on therapy. TCM consider that CP is in the category of "Jinglin" , "baizhou" and "laolin" . It' s start with moist heat afferent collaterals, stagnation of blood and qi, invalidism form sign of renal deficiency and moist heat hinder. In laboratory indexes, SOD can clean out Superoxide radical anion O_x~- to protect cell immunity damage, therefore it' s very important for the oxidation and antioxidation to balance in our body. The research shows that male infertility patient compare with health adult, the activity of SOD and the acrosomal enzyme is much lower, changes of semen SOD and acrosomal enzyme may be one of the reason for mail infertility. WHO consider that infertility caused by immunity is more valuable in clinic to test by MAR rather than simply tested by AsAb in the serum. In the infection of genital tract index,neutrophil elastase (NE) in seminal plasma can be an objective and effective index in screening and diagnose male genital tract infection. This experiment aimed to observe Cleaning Heat and Nourishing Kidney methods in clinical and rat' s effectiveness using NIH-CPSI, CASA, AsAb and neutrophil elastase index. It also observes a better way of improving CP patient' s sperm and living quality, providing an effective and economical scheme in treating CP with asthenospermia. Methods: This experiment composes in clinical and animal experiment. In the clinical observation we' re using methods of own control on experimental group and control group before and after the experiment, also own control on experiment group with control group. We used student-t test or x2 test for statistics methods. Asthenospermia caused by CP patients are collected between Sep, 2004-Jan, 2005 from The First Affiliated Hospital of Guangzhou TCM University during the visit, belonging to stagnated heat and internal resistant syndrome in TCM. There' re 60 patients with these diagnostic criteria, divide into experimental group and control group randomly with 30 patients each. General information and laboratory index shows no significant difference, which are comparable. We give experiment group Clearing-Heat and Nourishing-Kidney method Herb twice a day. And give control group Blood-Activating and Stasis-Eliminating Methods herbs twice a day. We Record down the NIH-CPSI, EPS-WBC, CASA, MAR and NE readings. In the animal experiment we observe changes in rat' s EPS-WBC, CASA, and SOD in seminal plasma' s level after the experiment. We also taking prostate gland in microscopic examination, analysis changes in histotype to exam the effectiveness of Clearing-Heat and Nourishing-Kidney method, Blood-Activating and Stasis-Eliminating Methods and Floxacin to CP. All the data are examined by using SPSS 10.0 software pack.Results: NIH-CPSI, EPS-WBC, CASA and NE shows great improvement in the experimental group (P<0. 05). AsAb with improvement but no significant difference (P>0.05). Compare experiment group with control group we find...