The Relation Between The Expression Of Survivin, Bax, Caspase-3 And HTERT In Condyloma Acuminatum And Cell Apoptosis And The Clinical Prognosis

Condyloma acuminatum(CA) is a kind of common sexually transmitted disease caused by human papilloma virus(HPV). the incidence of CA is the second high in sexually transmitted disease, and its incidence is higher gradually in recent years. The clinic behaves of CA is mainly cauliflower or papilloma proliferation in genitals parts, the warts of the minority of CA may hyperplasis excessly in short phase, which forms giant condyloma acuminatum (Buschke-loewenstein tumor). CA is a kind of benign proliferation disease, but in a small proportion perhaps progress to cancer. The infectivity of CA is high, and it does harm heavy to society and family, so it can harm the body and mind health of CA patients. The clinical treatment of CA is very difficulty and it may recur very easily after treatment, which has a great effect on its spread and popularity and the control on sexually transmitted disease is difficult, therefore more and more people pay attention to CA.In the field of tumor study in recent years, the study about cell apoptosis and telomerase has become a focus in medical circles. More and more datas also indicate that tumor is not only proliferation and differentiation abnormal, but also apoptosis abnormal. Cell apoptosis is controlled by a lot of genes, survivin has recently been identified as a novel inhibitor of apoptosis, and it has also positive correlation with cell proliferation, blood vessel formation. bax is the gene promoting apoptosis widely researched in bcl-2 family. caspase-3 is one of the key executors of the lower process...