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Dongzhimen Hospital Integrative Medicine In The Diagnosis And Treatment Of The Cross-sectional Study Of Acute Myocardial Infarction

Posted on:2004-09-20Degree:DoctorType:Dissertation
Country:ChinaCandidate:Y T FangFull Text:PDF
GTID:1114360092486112Subject:Integrative Medicine
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Acute Myocardial Infarction (AMI) is one of the most common emergency cases. It is characterized by sudden onset, rapid development, and high fatality rate. In the recent couple of decades, due to the introduction of deeper knowledge and improved methodology and the continuous intervention of innovated technology, western medicine has obtained breakthroughs in the treatment of AMI. The hospitalized fatality rate of AMI has dropped from around 15% to less than 10%.In the recent decades, Traditional Chinese medicine (TCM), especially Integrated Chinese and Western Medicine, has had extensive researches on the clinical and practical foundation of treating AMI, and has obtained remarkable achievements. However, most of the research achievements have not been proven by further clinical and experimental work. These achievements also lack the verifications of multi-center, great-sample and clinical trials. Since the record of TCM in evidence-based medicine (EBM) is null, the "Guidelines for the Diagnosis and Management of Patients with Acute Myocardial Infarction", established in 2001, did not mention TCM. In a period of increasingly popularized EBM, overlooking points such as the summarization of the highly repetitive treatment experiences, the most basic clinical experiments, and the verifications of multi-centered and great-sample clinical trials, has limited the clinical effects of TCM to a certain extent and affected the public acknowledgement of western medicine and the world on the treatment characteristics of TCM. An investigation research report last year revealed that in the year 2000, the hospitalized fatality rate of AMI in 4 first-grade, first-class TCM hospitals is apparently higher than that of first-grade, first-class western medicine hospitals(15.35% vs 6.98%), and it is still halted in the level of pre-reperfusion treatment era. Therefore, lowering the hospitalized fatality rate of AMI and increasing the clinical effects have become a priority in TCM hospitals in the Beijing area for improving emergency clinical work.In the recent couple of years, the material living of people have improved apparently, the Chinese medicine syndromes of some diseases have changed. Have the Chinese medicine syndromes of AMI changed? Do the past treatment ideas of Chinese medicine (ex. invigorating qi and stimulating the circulation of blood) need to change relatively? Therefore, there is a need to re-understand the syndromes of AMI.This research is launched in accordance with the above-mentioned points. It mainly discussed the gap between treatment measure and "Guidelines for the Diagnosis and Management of Patients with Acute Myocardial Infarction" ,the developing trend on symptomatalogy on TCM in the first three weeks in the Dongzhimen Hospital .Result: ①.A total of 122 effective cases were gathered, with an AMI hospitalized fatality rateof 13.11%. There is a trend of improvement in the standardized treatment of western medicine through the years, but problems such as inability to acknowledge and practice EBM and the management guidelines are still present. COX regression reveals the failure of β-B and herbs that stimulate the circulation of blood in lowering the fatality rate of AMI, in contrast to the analysis of the Pearson chi-square test. ② The standardized treatment group can better prevent complications, protect the cardiac functions, and limit the infarction area compared to the non-standardized treatment group. There is an apparent difference between the two groups. (LVEF 58.06±6.34% vs 53.40±6.34%,P<0.05;QRS Scores 3.06±0.93 vs 3.90±1.41, P<0.05). ③ From the Chinese medicine syndrome studies, hospitalized AMI patients without serious complications were observed for 3 weeks. Qi deficiency and blood stasis are only seen in the early stages of AMI(days 1-3). After 2 days, most patients mainly show signs of blood stasis. Blood stasis is present during the whole process of the disease. This is different from past knowledge of the disease.Conclusion:In the Dongzhimen Hosp...
Keywords/Search Tags:Acute Myocardial Infarction, Therapeutics, Symptomatalogy on TCM
PDF Full Text Request
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