The Effectiveness Of The Treatment In Functional Dyspepsia For Singaporeans With The Syndrome Of Liver-qi Stagnancy And Damp Retention By Applying Chinese Herbal Medicine In Soothing The Live-qi, Removing The Dampness And Regulating The Stomach Together W

AIM:The purpose of this study is to explore the therapeutic effect of Chinese herbal medicine insoothing the liver-qi, removing the dampness and regulating the stomach, and psychologicalefficacy for the treatment of Functional dyspepsia (FD) for Singaporeans, whom with theTCM syndrome of liver-qi stagnancy and dampness retention.METHODS:50 subjects, being randomized divided into two groups. The treatment group had beenrespectively taking herbal medicine, Chaizhu Xiaopi Decoction and integrated withpsychological treatment; whilst the control group just simply consuming herbal medicine,Chaizhu Xiaopi Decoction as an intervention for 4 weeks. All the subjects, before and aftertreatment, were examined with FD symptoms scale.RESULTS:In treatment group, there were 19 significantly improved, 3 effective and 2 cases had noimprovement, the total effective rate of the treatment group were 91.67%; whilst in thecontrol group, there were 6 significantly improved, 11 effective and 5 cases had noimprovement, the effective rate in the control group were 77.28% respectively. Compare thetreatment group to the control group, before and after treatment, treatment group had showeda significant different improvement in the symptoms. (P<0.01) This indicated that theefficacy of Chaizhu Xiaopi Decoction accompanied by psychological treatment is muchbetter than only consumed Chaizhu Xiaopi Decoction in control group.In comparison, within the treatment group and control group, it was very significantdifference in the efficacy before and after treatment.(P<0.01)This indicated that both ChaizhuXiaopi Decoction and Chaizhu Xiaopi Decoction applied together with psychologicaltreatment both were effective in treating FD syndrome of liver-qi stagnancy and dampretention.The total scores of treatment group in FD symptoms scale, before and after treatment groupwere 20.38±6.68,6.75±3.77 respectively; whilst that of control group were 21.05±6.79, 10.50±4.52 respectively. The improvement on some of the single FD symptoms, such as bloating and abdominal distension, depression and bowel movement problem in treatment group were very significantly improved as compare to the control group, (P<0.01). Other than these three symptoms, early satiety, belch, bitter and dry in mouth, upper abdominal pain, the need to sigh to release stress, poor appetite and lethargy were not significantly difference between two groups. (P>0.05)CONCLUSION:The efficacy of the traditional Chinese herbal medicine based on the TCM principles of , Chaizhu Xiaopi Decoction, together with psychological intervention, for FD treatment has obviously excelled that of control group which only applying Chaizhu Xiaopi Decoction. The treatment group could not only alleviate FD symptoms but also effectively relieve depressive condition of the patients. This suggested that psychological intervention for FD treatment is important, and more research is needed and physicians should apply it into clinical practice more for better effect.