Mining, Knowledge-based Uncertainty Reasoning "treatise On The Side Card

This project presents a uncertain inference method which is used for the quantization and data mining of prescriptions and syndromes knowledge in treatise on febrile diseases.With the successful application of uncertain inference method,it will provides a new idea for the quantitative expression about prescriptions and syndromes knowledge of TCM.1 ObjectiveThis project starts with prescription study, and uses the method of combing artificial intelligence technology and knowledge base. It will realize quantitative expression ofprescriptions and syndromes knowledge in treatise on febrile diseases by mathematical model and make the learners reproduce the process of syndrome differentiation about zhongjing through the analysis of the prescription.2 Method2.1 Uncertain InferenceUncertain inference is based on uncertain knowledge and evidences. Through the use of uncertain knowledge and initial evidences of departure, it has infered the results which is reasonable or close to the thinking process of a reasonable conclusion. Because traditional Chinese medicine is fuzzy, uncertainty and incomplete features, leading to the same disease and syndrome are not the only solution. dialectical reasoning the knowledge uncertainty, background knowledge of experts and other issues is inconsistent.Therefore, Uncertain inference is needed to study traditional Chinese medicine.2.2 Knowledge TechnologyKnowledge database is based on the review of literature concerned and refer the knowledge of basic theory of TCM, chinese pharmacy, chinese diagnostics and chinese internal medicine. It mainly includes the knowledge of medicine effects, such as pesticide effect Knowledge base, pesticide effect with symptoms Knowledge base, pesticide effect with syndrome elements Knowledge base, syndrome elements with syndromes Knowledge base.The logical rule of Knowledge base is based on TCM theory.Through the quantitative expression of prescriptions and syndromes in treatise on febrile diseases,we can find some new understanding which increase Knowledge base.2.3 Algorithm Design and Software Development Dosage is the basis of efficacy, but also affect the prescription effect of the important factors. As the drugs are different in nature, the extent of their drug use would be very different from the actual amount in the recipe,and it is difficult to determine both the amount of the intensity, because of the lack of comparability. Chinese medicine theory as a guide to design specific mathematical algorithm first dosage of the drug were normalized, put forward the "dose intensity" concept, made between the various drugs and drug efficacy has been comparable strength analysis. Pharmacodynamic interaction between the two while the system strength calculation, the introduction of the "closeness" concept.Two drugs in the air, taste, meridian and the efficacy of such factors as the integrated area were closed to the level of gas in accordance with the requirements, different repulsion of the principle of gas, close to the greater degree of synergy between the drugs the greater the contrary, the smaller the close degree of drug antagonism between the greater its efficacy in relationship to calculate the weights reflect, to make the results more is accurate. Finally, realize that can be run in the windows system to study the starting point of Chinese Medicine Prescription Intelligent Analysis System (CPIAS). Treatise on the Prescription and Syndromes information data, by analysis with the method of indexing consistency of treatment to enter prescriptions intelligent analysis system for quantitative analysis to determine the composition of the prescription drug contribution, comprehensive prescription Drug gas intensity, integrated Yaowei prescription strength, prescription comprehensive meridian strength, prescription strength of various effects, for the current clinical manifestations of disease and syndrome screening the effectiveness of the most adapted intensity, in screening the most suitable basis for the effectiveness of strength analysis and prescriptions on the evidence related factors predict prescription indications, and to determine the prescription against the clinical manifestations (symptoms and signs) of major and minor.3 Result3.1 Carry out the quantitative analysis of prescriptions and syndromes in treatise on febrile diseasesIn this study,mathematical modeling and uncertainty through the combination of methods of reasoning, the relevant factors surrounding the prescription effect relationships(dose-effect relationship, relationship efficacy,effect climate relations, effective relationship factors, prime card relationships) of the quantitative method to achieve the Treatise on the 112 Prescription and Syndromes knowledge,qua-litative and quantitative expression.Basically consistent with later results not only physician on the Treatise on the general knowledge, but also for interpretation, Treatise on the Prescription and Syndromes information provides meaningful data to support. Through quantitative expression of 112 prescriptions with interaction strength,we achieve the ranking of Monarch, Minister,Assistant and Guide in treatise on febrile diseases.Through quantitative expression of four natures, five tastes and channel tropism combined with 112 prescriptions,we found the law of composition with four natures and five tastes, and found the features of channel tropism. Through quantitative expression of syndrome differentiation knowledge combined with 112 prescriptions,we found the dialectical thinking of zhong-jing.Through application of CPIAS in no measurement device and prescription dismantlement research, it will expand the application range of CPIAS.3.2 The exploration of knowledge engineer of TCMThis study attempts to establish thousands of Chinese medicine knowledge, and is successfully applied in the Chinese Medicine Prescription Intelligent Analysis System. Although the knowledge could not meet the demand of study of Chinese intelligence,but the knowledge base fouded by the method and principle was confirmed successfully and it could be promoted and improved. The project probes a number of issues which was found in research.4 ConclutsionThe breakthrough point of modernization about Traditional Chinese Medicine Theory is quantitative and digital expression of theory. This is the only way wich could maintain its own characteristics and keep healthy development with the times.Through the quantitative expression and knowledge mining with uncertain inference method used in treatise on febrile diseases,it is proved that research programs is feasible,which has solid foundation and potentiality.