The Pediatric Clinical Application Of Professor Chen Zhaoding’s Academic Ideology Of Spleen And Stomach And The Study In Treatment Of Children With Abdominal Purpura

This study basically inherited from the clinical experience of Professor Chen zhaoding, whose academic ideology of spleen and stomach to treat children’s diseases. In order to inherit the experience of famous doctor of traditional Chinese medicine should analysis both his academic origin and background.During the pediatric clinical practice, Professor Chen studied ancient classics, took the strengths of each, gradually formed a "spleen and stomach-centric" dialectical thinking and drug characteristics. A distinguishing feature of treating pediatric diseases is pay attention to spleen and stomach; propose spleen’s exercise for health.The main source of Professor Chen’s thoughts came from academic ideology of spleen and stomach of Mr. Wang Pengfei. Professor Chen constantly carried on the academic thought of Mr. Wang during the clinical practice. Chen not only paid attention to the spleen and stomach, but also attached importance to qi and blood, constantly opened up the field of treatment of pediatric. He established gastroscopy office, gastrointestinal electrogram office and traditional Chinese medicine pediatric ward of spleen and stomach disease, started the diagnosis and treatment of the combination between the differentiation of syndromes and the differentiation of disease in pediatric spleen and stomach disease, and the combination between macro and micro differentiation of syndromes. He put emphasis on clinical research, advocated the reform of preparation form, and continually enriched the pediatric prescriptions, so more and more simple, convenient and cheap herbs can be widespread use for children. At the same time, his research had achieved certain results thus promoting the development of traditional Chinese medicine pediatric subjects.Even though Professor Chen’s academic ideology originated from the old famous Chinese medicine doctor’s clinical experience, he paid more attention to tradition and innovation, especially in the treatment fields of pediatric spleen and stomach disease and difficult diseases. This study gives a summary from following aspects.1. Professor Chen considers that children diarrhea disease is mainly caused by hypofunctioning of spleen and stomach. He paid attention to the types in determination of treatment based of differentiation of syndromes. With his many years of experience in treatment, he pointed out the property and flavor, and meridian oriented effect in Chinese medicine, tried to have a deep understanding of the intention of prescription, use the prescription compatibility to reflect types to differentiation of syndromes.2. Pay attention to the methods of pediatric gastrocopy, to the research of Hp infection, and to treatment in pediatric stomach dampness heat with Chinese medicine.3. Professor Chen believed that pediatric ulceration belongs to stomachache category which means the stomachache lesions in stomach, close to liver and spleen, with the cause of cold, heat, diet, weary, blood stasis, etc. Treatment should start from regulating stomach, invigorating spleen, regulating qi, relief of pain, and activating blood circulation to remove blood stasis.4. Professor Chen thinks that it is difficult to treat anorexia nervosa, to distinguish deficiency and excess or both of them are particularly important. Treatment should pay attention to regulating the spleen and stomach function. Prescription composition:Rhizoma Polygonati, Fructus Amomi, Jian Qu, Jiao Baishu, Radix Arnebiae.5. Treatment for suckling hepatitis syndrome:Chen believes the disease usually caused by the damp-heat retained in the womb during maternal fetal pregnancy, or infects the damp-heat after birth. The damp-heat resistant in the spleen and stomach, fumigate in liver and gallbladder, Gas-poor, blood stasis, disorder in soothing liver and gallbladder and then cause jaundice. Removing heat and dampness, normalizing the gallbladder function to treat jaundice, soothing liver and invigorating spleen, promoting blood circulation to remove obstruction from meridians are the basic law of Professor Chen’s treatment experience of jaundice.6. Attention Deficit Hyperactivity Disorder (ADHD) is primarily characterized by the co-existence of attentional problems and hyperactivity. Professor Chen particular emphasis on pediatric treatment with different symptoms according to Chinese medicine, by adjusting the body’s organs, meridians, qi and blood function and overall functional status to improve children’s social and natural environment adaptability.7. Treatment of allergic purpura nephritis:with years of clinical experience of allergic purpura nephritis, Professor Chen divided the disease etiology and pathogenesis into three causes, as interior retention of damp-heat, blood stasis with qi stagnation, and deficiency in the lung caused by chronic diseases. In addition, the diminished function of children, invasion of the body by wind and exogenous pathogenic factors. With numerous clinical manifestations, the disease usually taken place in lung, spleen and kidney. Chen would use Qingdai, Radix Arnebiae, the root bark of the peony tree, Herba Patriniae, Semen Phaseoli, etc. for treatment in clearing heat, increasing secretion of urine and removing heat from blood to stop bleeding.8. Treatment for pediatric Banti’s syndrome:Professor believes that the causes of this disease are qi stagnation, blood stasis and indigestion. With the pathological features of children, activating blood circulation to remove blood stasis and regulating qi flow as primary achievements, it will certainly have a bad effect on treatment of qi just because of Children’s undetermined qi circulation and tender organs. These are the prominent pediatric clinical experience of Professor Chen’s ideology of spleen and stomach.This study using Professor Chen’s ideology to study children’s abdominal allergic purpura in clinical application; reflecting the ideology of the combination of macro and micro dialectic, identified diseases and syndromes, and the follow up survey of children’s disease; delving into his clinical experience; proposing standardized research programs, inheriting and carrying forwards Professor Chen’s academic experience.Clinical analysis in 120 cases of children’s abdominal allergic purpura.Cases enrolled in this issue since January 2001 to March 2010:120 cases of children, male: 64cases, female:56 cases. Youngest 4 years old, oldest 16 years old.3 to 7 years old:19 cases; 8 to 12 years old:68 cases; over 12 years old:33cases. The results of gastroscopy show: Esophagitis:4 cases; Gastritis:9 cases; Duodenitis:12 cases; Stomach and Duodenitis:63 cases; Gastrelceosis:2 cases; Duodenal ulcer: 30 cases. With renal injury:43 cases, accounting for 35.8%. Infection-related factors:Mycoplasma infection:9 cases; Streptococcus infection:8 cases; Tuberculosis:6 cases; Helicobacter pylori infection:2 cases; Herpes simplex virus:1 case, CMV infection:1 case.The composition ratio in 120 cases of children with TCM type:Based on clinical symptoms, divided into four diagnostic syndrome types, those are:(1) The pathogenic factors invade the interior of the body while the stomach is weak,23 cases, and accounting for 19.1%.(2) Damp-heat in spleen and stomach,74 cases, accounting for 61.7%.(3) Injury to superficial venules,20 cases, accounting for 16.7%.(4) Yang deficiency of spleen and kidney,3 cases, accounting for 2.5%.The short-term and follow-up six months of long-term treatment efficacy among the 60 cases of damp-heat in spleen and stomach type.Damp-heat in spleen and stomach type selected 60 patients is randomly divided into 2 groups, each of the treatment and the control groups get 30 patients. It is statistical analyzed and comparable.Treatment group:cured 20 cases (66.7%); improved,9 cases (30%); invalid,1 case; total efficiency,96.7%.Control group:cured,20 cases (66.7%); improved,8 cases (26.7%), invalid,2 case; total efficiency,93.3%.The statistical analysis P> 0.05. There are 2 patients with kidney damage in the control group, none in the treatment group. Objective:This study using Professor Chen’s ideology to study children’s abdominal allergic purpura in clinical application; reflecting the ideology of the combination of macro and micro dialectic, identified diseases and syndromes, and the follow up survey of children’s disease; delving into his clinical experience;proposing standardized research programs, inheriting and carrying forwards Professor Chen’s academic experience.Methods:Choosing 120 cases of children’s abdominal allergic purpura with gastroscopy, which can reflect the academic ideology of combination treatment between macro and micro differentiation of syndromes, and also between the differentiation of syndromes and the differentiation of disease in pediatric spleen and stomach disease. However, to the children whose damp-heat in spleen and stomach will be selected 60 cases of them, randomly divided into 2 groups, each of the treatment and the control groups get 30 patients. The treatment group use "Qing Zi Zhi Tong Decoction" with Western medicine treatment, the control group will only use Western medicine treatment. The total treatment course takes about 2 to 4 weeks; it need to fill out clinical watch list, use SPSS software for statistical processing, analysis the improvement differences between the treatment and the control groups. Get another follow-up six months of long-term treatment efficacy, observe and analyze the kidney involvement.Results:Clinical analysis in 120 cases of children’s abdominal allergic purpura.Cases enrolled in this issue since January 2001 to March 2010:120 cases of children, male:64, female:56 cases. Youngest 4 years old, oldest 16 years old.3 to 7 years old:19 cases; 8 to 12 years old:68 cases; over 12 years old:33 cases. The results of gastroscopy show:Esophagitis:4 cases; Gastritis:9 cases; Duodenitis:12 cases; Stomach and Duodenitis:63 cases; Gastrelceosis:2 cases; Duodenal ulcer:30 cases. With renal injury:43 cases, accounting for 35.8%. Infection-related factors: Mycoplasma infection:9 cases; Streptococcus infection:8 cases; Tuberculosis:6 cases; Helicobacter pylori infection:2 cases; Herpes simplex virus:1 case, CMV infection:1 case.The composition ratio in 120 cases of children with TCM type:Based on clinical symptoms, divided into four diagnostic syndrome types, those are:The pathogenic factors invade the interior of the body while the stomach is weak,23 cases, and accounting for 19.1%.Damp-heat in spleen and stomach,74 cases, accounting for 61.7%.Injury to superficial venules,20 cases, accounting for 16.7%.Yang deficiency of spleen and kidney,3 cases, accounting for 2.5%. The short-term and follow-up six months of long-term treatment efficacy among the 60 cases of damp-heat in spleen and stomach type.Damp-heat in spleen and stomach type selected 60 patients is randomly divided into 2 groups, each of the treatment and the control groups get 30 patients. It is statistical analyzed and comparable.Treatment group:cured 20 cases (66.7%); improved,9 cases (30%); invalid,1 case; total efficiency,96.7%.Control group:cured,20 cases (66.7%); improved,8 cases (26.7%), invalid,2 case; total efficiency,93.3%.The statistical analysis P> 0.05. There are 2 patients with kidney damage in the control group, none in the treatment group.Conclusion:1. The study selected 120 clinical cases, analysis the TCM characteristic of abdominal allergic purpura and the composition ratio of types, and deepens the study.2. In particular, further study to the different characteristics of macro-and micro-endoscopies of damp-heat in spleen and stomach type, which gets a large percentage in the abdominal allergic purpura.3. Compared the short-term effect between Western medicine treatment and Western medicine combine with "Qing Zi Zhi Tong Decoction" treatment for damp-heat in spleen and stomach type of abdominal allergic purpura.4. Preliminary understanding of the combination therapy of abdominal allergic purpura and the damage to kidney in long-term effect.