| ObjectiveOn the basis of research on ancient and modern literature, spleen and kidney Turbidness proposed joint enemas, oral Shengqingjiangzhuo capsules, spleen qi deficiency with conventional treatment, patients with chronic renal failure syndrome damp conducted a prospective observational study To evaluate the clinical efficacy of kidney and spleen Xiezhuo treatment of chronic renal failure. Follow the simple randomized control methods, an objective assessment of the degree of spleen and kidney Turbidness improve the indicators of chronic renal failure. Hope to provide a relatively precise clinical efficacy of the new method with chronic renal failure can be generalized treatment.Methods①clinical performance:Spleen and Kidney Turbidness combined Western and Western medicine alone compared two groups of treatment programs can effectively reduce the symptoms of chronic renal failure in total points, and with the spleen and kidney Turbidness have chronic renal the degree of clinical improvement is more apparent failure patients (P<0.05). In common clinical symptoms, there are some differences in the degree of improvement of different symptoms in different treatment regimens. Treatment group in limb edema, lassitude, shortness of breath lazy words, clear and long nocturnal four main symptoms were significantly improved, compared to a significant difference (P<0.05) before and after treatment; control group lassitude, shortness of breath lazy words, and other major symptoms were significantly improved, compared to a significant difference (P<0.05) before and after treatment.②Check in laboratory:For comparison with renal function associated laboratory parameters, spleen and kidney Turbidness combined Western and Western medicine alone can significantly reduce BUN, SCr, HGB level, and joint spleen and kidney Turbidness the degree of improvement was better than Western medicine Western medicine treatment (P<0.05). Both groups significantly increased glomerular filtration rate (GFR), reduce cholesterol,(P<0.05), and the degree of improvement in both groups, a considerable effect (P>0.05). Spleen and kidney Turbidness combined western medicine can significantly lower blood β-microglobulin, cystatin C levels, while little change in western medicine to improve the efficacy of the treatment group than the control group (P<0.05). Both groups changed little effect on triglycerides (P>0.05).Conclusion①clinical performanceAfter different treatment regimens, both groups of patients before treatment compared to treatment with the total symptom score improved to varying degrees, by comparative analysis, which improved with the use of traditional Chinese medicine decoction symptom score in patients treated with more significant after two treatment integral comparison group analysis showed that the patient’s symptoms, the treatment group improved symptom scores than the control group. Effect on symptoms in two groups of patients after treatment were analyzed can be found, after treatment, the efficacy assessment, the proportion effective to treat patients as much, because the shorter course of treatment, few patients can achieve markedly or cure effect. Comparative analysis of the two groups were generally no significant difference in the efficacy of symptoms, suggesting that the two groups in terms of efficacy evaluation of symptoms, a considerable improvement effect②Check in laboratorySpleen and kidney Turbidness combined with Western medicine in the treatment of chronic renal insufficiency good clinical efficacy therapy can significantly improve a patient’s limb edema, lassitude, shortness of breath, clear and long lazy Speaking nocturnal symptoms and improve to some extent patients BUN, SCR, GFR, CysC, serum β-microglobulin and other related indicators, and for the improvement of SCR, CysC, serum β2-microglobulin and other indicators show a greater advantage.③spleen and kidney Turbidness combined Western medicine treatment of chronic renal failure clinical efficacy more precise, to the implementation of standardized operation, easy to spread, there are broad prospects for clinical application. |