Evaluation Of Changes Of Foveal Thickness And Mean Sensitivity After Uncomplicated Phacoemunification

PartⅠEvaluation of Changes of Foveal Thickness and Mean Sensitivity after Uncomplicated Phacoemulsification in Patients with Senile CataractObjective:To evaluatethe changes of foveal thickness (FT)and visual functionin patients with senile cataract after phacoemulsification, to correlate morphologic changes with visual functional outcomes.Methods:One hundred and twenty-two patients with senile cataract undergoing phacoemulsification in one eye were included. All patients had clinical assessment, spectral-domain optical coherence tomography(OCT), and microperimetry-1(MP-1) examination preoperatively and at weeks1,4, and12postoperatively. TheFT and mean sensitivity (MS) at different time intervals were analyzed. Best-corrected visual acuity (BCVA) was recorded at each visit. Pseudophakic cystoid macular edema was defined as an increase of FT on OCT>30%from preoperative baseline.Results:Preoperative FT was231.7±8.4μm, the FT was246.0±13.9μmat1week,234.3±18.2μm at1month, and231.9±8.7μm at3month after the surgery. The FT at lmonth after surgery showed significant increase than before, P<0.05, but nosignificant increase at3month. The MS was15.1±4.5dB at1month, significantly increased than before, P<0.05. The LogMAR BCVA was significantly decreased after surgery, P<0.05.Conclusions:The cataract surgery had minimal effect on the eyes with senile cataract, and the MS and BCVA were both improved after surgery. Part ⅡEvaluation of Changes of Foveal Thickness and Mean Sensitivity after Uncomplicated Phacoemulsification in Patients with DiabetesObjective:To evaluatethe changes of FTand visual functionin patients with diabetes after phacoemulsification, to correlate morphologic changes with visual functional outcomes.Methods:One hundred and two patients with diabetes undergoing phacoemulsification in one eye were included. All patients had clinical assessment, OCT and MP-1examination preoperatively and at weeks1,4, and12postoperatively. TheFT andMS at different time intervals were analyzed. BCVA was recorded at each visit. Pseudophakic cystoid macular edema was defined as an increase of FT on OCT>30%from preoperative baseline.Results:Preoperative FT showed significant difference between the diabetics and the controls, P<0.05. The FT at lmonth and3month was significantly increased than before in diabetes, P<0.05.The preoperative MS was significantly worse in the diabetic group than in the control group, P<0.05. The MS at1week,1month, and3month was significantly improved than before, P<0.05. The mean LogMAR BCVA at1month and3month was significantly decreased than before, P<0.05. There were5patients who developed cystoid macular edemaat1month,4of which having the diabetes more than10years.Conclusions:Eyes of diabetic patients present higher FT and a higher incidence of cystoid macular edema after cataract surgery on OCT examination compared to eyes of healthy controls, associated with a loss of visual function at1month. Part IIIEvaluation of Changes of Foveal Thickness and Mean Sensitivity after Uncomplicated Phacoemulsification in Patients with High MyopiaObjective:To evaluatethe changes of foveal thickness (FT)and visual functionin patients with high myopia after phacoemulsification, to correlate morphologic changes with visual functional outcomes.Methods:Sixty-seven patients with high myopia undergoing phacoemulsification in one eye were included. All patients had clinical assessment, OCT and MP-1examination preoperatively and at weeks1,4, and12postoperatively. TheFT and MS at different time intervals were analyzed. BCVA was recorded at each visit. Pseudophakic cystoid macular edema was defined as an increase of FT on OCT>30%from preoperative baseline.Results:Preoperative FT in high myopia (211.7±13.9μm) was significant thinner than the controls, P<0.05. The FT at1month and3month were250.8±31.0μm and229.4±22.6μm, both of which were significantly increased than before, P<.05.The preoperative MS (6.6±2.5dB) was significantly worse in the high myopia group than in the control group, P<0.05. The MS at1month (13.4±3.7dB) and3month (13.3±3.5dB) was significantly improved than before, P<0.05. The mean LogMAR BCVA at1month and3month was significantly decreased than before,P<0.05. There were3patients who developed cystoid macular edemaat1month.Conclusions:Eyes of diabetic patients present higher CFT and a higher incidence of cystoid macular edema after cataract surgery on OCT examination compared to eyes of healthy controls, associated with a loss of visual function at1month, with limited visual recovery at3months.