Thiocyanation Of Aromatic And Heteroaromatic Compounds And Aromatization Of Pyrazolines

In this thesis, the thiocyanation of indoles, pyrrol, and aromatic amino compounds was carried out using I₂O₅ as an oxidant, and oxidative aromatization of 1,3,5-trisubstituted pyrazolines the corresponding pyrazoles was achieved with Mn(OAc)₃·2H₂O. This thesis is divided into three parts.The first part outlines the recent progress in the application of hypervalent iodine reagents in organic synthesis and total synthesis of many complicate natural products, and in the thiocyanation of unsaturated alkenes, alkynes and carbonyl compounds. The transformation of the thiocyanate group and the application of thiocyanation in organic synthesis were involved.The second part reports my research on the thiocyanation of indoles, pyrrols, and aromatic amino compounds using ammonium thiocyanate as a thiocyanation agent and I₂O₅ as an oxidant. The solvent effects and react conditions were examined. Products were obtained in good yield.The third part describes the oxidative aromatization of 1,3,5-trisubstituted pyrazolines to the corresponding pyrazoles by Mn(OAc)₃·2H₂O.