Observation On The Regularity Of Traditional Chinese Medicine In The Treatment Of External Application Of Pressure Sore And The Clinical Efficacy Of Compound

Objective:1.first bedsore external treatment by analyzing 75 prescriptions (common medicine, commonly used for, formula rule and network chart shows), summarizes the treatment of traditional Chinese medicine treatment of bedsore of drug law, puts forward the new, potential or prescription drugs for, to enrich the content of traditional Chinese medicine for external use.2.we will compound cortex phellodendri liquid applied in patients with pressure ulcers, were observed before and after medication wound healing situation (time, wound size and laboratory index), verify the effectiveness of the compound cortex phellodendri liquid treating bedsore.Materials and methods:Sources:Data of ten thousand domestic database Knowledge service platform (Wangfang Data) and China hownet (China National Knowledge Infrastructure, CNKI) all published as of December 31,2014 by the prescriptions of traditional Chinese medicine external treatment to treat bedsore literature; Methods:through "treatment of traditional Chinese medicine", "external treatment" and "pressure ulcers" keyword, screening requirements with 133 references, and then to "prescription content complete taste (complete)" condition of the final selection 75 prescriptions, drug law analysis, mainly for medication frequency statistics, association on the evolution of the contact and potential new prescriptions generated.Tools:inheritance of traditional Chinese medicine platform V2.5 version (traditional Chinese medicine research institute of China institute of traditional Chinese medicine developed)Clinical research:select the third affiliated hospital of Beijing medical university,90 cases of bedsore patients randomly divided into two groups, were given compound fluid of cortex phellodendri, sulfadiazine silver lipid water-binder dressing (trade name:youtube) for external use, observe two groups before and after medication wound situation (healing, improve the time, the size of the wound, and laboratory index).Results:1.75 entry outside treat Chinese traditional medicine prescription in this study, involving 118 kinds of drugs, the top 15 taste of one of the most common drugs is:borneol, dragon’s blood, frankincense, rhizoma coptidis hu, angelica, myrrh, cortex phellodendri, radix et rhizoma rhei, radix angelicae, radix arnebiae seu lithospermi, safflower, calamine, catechu, liquorice, pearl. And more drugs to invigorate the circulation, boils, mainly the production of. Commonly used in drugs and drug combinations frankincense, dragon’s blood, borneol, myrrh; Frankincense, angelica, myrrh; Frankincense, dragon’s blood, myrrh; Frankincense, dragon’s blood, borneol; Frankincense, borneol, myrrh, the most common army invigorate the circulation of the production. Through software integration of hierarchical clustering method, entropy clustering can obtain can combine ChengXinFang potential combination. These combinations of commonly used medicine astragalus gallnut_ _dilong, radix arnebiae seu lithospermi licorice angelica dahurica, etc., and some not commonly used drugs, such as the phoenix dress folk medicine. After these combinations by further compatibility can be generated and the prescriptions of 75 different New Zealand.2. The compound cortex phellodendri fluid can effectively promote the bedsore wound healing, shorten the healing time. Reduce wound PH value; Improve wound hydroxyproline and the content of serum free glutamine.