| Objective:By the mean of questionnaire survey, this paper studied resident’s awareness of stroke’s inducing factor in Beijing,in this way we can provide fundamental date and theory basis for community general practitioner’s stroke supervise, and enhance the popularization of stroke’s information among residents. By the mean of researching IRAK-M’s regulated effect for cerebral hemorrhage liver damage, discussed the protective ability of Ditantongyu method for cerebral hemorrhage liver damage, and the Ditantongyu method’s intervention for the expression of IRAK-M, so we can provide experimental basis for clinical promotion ofDitantongyu method.Method:1.Clinical research:By the mean of questionnaire survey, we collected 116 inhabitant’s the effective questionnairewho comply with the requirements of the investigation in Datun community, Chao-yang district, Beijing city, during October 15, 2014 to December 30,2014.In different standard of comparison, the count data are analyzed, counted by the ways of frequency distribution and percentage of records.2.Experimental studies:By building models of acute cerebral hemorrhage of SD rats, and in accordance with random number table method, the rats were randomly divided into TCM treatment group (Group T), cerebral hemorrhage group (Group C), sham surgery group(Group S), blank control group(Group B), and each group was further divided into 3 time-point sub-groups of 24,48 and 72h, detected IRAK-M protein expression levels in liver tissue and tumor necrosis factor-a(TNF-a) level of each group, and observed the results of HE staining of liver tissue of each group.Result:1. Clinical study:The average age of all respondents was 51.54 years old, and 45 to 59 years age group is maximum, and the number of women slightly more than men. Survey shows that people’s awareness for risk factors of stroke is generally low,the awareness of risk of hypertension factors is highest,but the awareness of genetic factors is lowest, and awareness level is different in different ages group, the middle-aged (that is between 45 to 59 years old) have the highest awareness; and different educational level effect the awareness of risk factors for stroke, college and above is the highest awareness crowd. 2. Experimental Study:IRAK-M expression of normal group’s ACH model was significantly lower than the sham operation group (P<0.05), but no significant difference in the 72h time point; at all the point of time, TCM group have a higher expression of IRAK-M in liver tissue than cerebral hemorrhage model group (P<0.05),and compared with the normal group and the sham operation group decreased slightly. As to TNF-a expression levels,cerebral hemorrhage model group were significantly increased at all time points compared with the normal group (P<0.01), the TCM group are lower at this time points compared with cerebral hemorrhage model group (P<0.05). And we found that Ditantongyu method could reduce the damage for liver.Conclusion:1. clinical study:common risk factors of Stroke are genetic, hypertension, diabetes, hyperlipemia, smoking, alcoholism, obesity and overweight, emotional and psychological factors, the survey found that the awareness of residents about risk factors for stroke is uneven, and the awareness of hypertension factor’s risk is highest, up 36.21 percent; and awareness of geneticfactors is lowest, only 12.93%. Therefore the hospital should strengthen themanagement ofchronic diseases such as stroke, related knowledge’s education,and the television broadcasting propaganda is a necessary way to popularize universal health knowledge, and gradually strengthen the concept of treating disease before you get it.2. Experimental study:IRAK-M protein levels may be the important factor to control LPS intracellular signal transfer to inflammation that caused by brain hemorrhage; Ditantongyu method can enhance the activity of IRAK-M, which inhibiting the release of inflammatory factor TNF-α, reduce the degree of liver damage in rats with hemorrhagic brain.
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