Clinical Effect Of Integrative Chinese And Western Medicine On Ischemic Stroke With Hypertension

Purpose： To explore the combination of traditional Chinese and Westernmedicine intervention hypertensionischemic stroke recovery period of phlegmand yin deficiency syndrome in patients with clinical efficacy.Material and method：1Subjects: the research adopts multi center, parallel group trial, using aspirin,aspirin intolerance or allergy can be used as the basic treatment of Westernmedicine for clopidogrel,ischemic stroke recovery period of phlegmand yindeficiency syndrome patients.2Grouping method: the subjects were recruited, case by standards, compliance,physical examination,examination ability to complete the screening, eligiblesubjects according to the proportion of1:1were randomlyassigned into clinicaltrials, including40cases of test group,43cases in the control group.3Interventions: treatment control group including Western Medicine Departmentof internal medicine therapy(aspirin or clopidogrel,0.1Qd,75mgQd), modernrehabilitation treatment, routine care, treatment for4weeks, the test grouptherapy include oral Chinese patent medicine (Hua Tuo zaizao pill8tid, ZhongjingSix Ingredient Rehmannia Pill8tid), Chinese medicine injection in the treatmentof acupuncture, massage therapy,, Western Medicine Department of internalmedicine therapy (aspirin or clopidogrel0.1Qd,75mgQd), modernrehabilitation,nursing.4Evaluation tool: select the recovery period of phlegm and blood stasis andevaluation of yin deficiency syndromescale, American National Institutes ofHealth Stroke Scale (NIHSS), the selected period,2weeks,4weeks,90days,180days for the information acquisition time point. 5Observation index: different point in time recovery period of phlegm and bloodstasis and evaluation of yin deficiency syndrome scale, NIHSS total scoredifference.6Statistical methods: descriptive statistics, paired samples t test, Wilcoxontest, Mann-Whitney U test, statistical analysis of data.Results：The patients in test group40cases, control group43cases, a totalof83cases. The test group2casesover time window;2cases in the controlgroup over time window. The final line scheme of test group38cases,controlgroup41cases, included in the PPS data set, a total of79cases.1The test groups (A) recovery period phlegm and yin deficiency syndromescoretotal score at2weeks,4weeks,90days,180days compared with thosebefore treatment improved, the difference was statistically significant (P <0.05). The test group patients with hypertension (A1) recovery period phlegmand yin deficiency syndrome score total score at2weeks,4weeks,90days,180days compared with those before treatment improved, the difference wasstatistically significant (P <0.05). The test group with no previous historyof hypertension (A2) recovery periodphlegm and yin deficiency syndrome scoretotal score in0-2compared with those before treatment improved, no significantdifference (P>0.05); improvement in0-4weeks,0-90days,0-180days afterthan before treatment, the difference was statistically significant (P <0.05).2The control group (B) patients phlegm and yin deficiency syndrome scoretotalscore at2weeks,4weeks,90days,180days compared with those beforetreatment improved, the difference was statistically significant (P <0.05).The control group patients with hypertension (B1) recovery period phlegm andyindeficiency syndrome score total score at2weeks,4weeks compared with beforetreatment improved, the difference was statistically significant (P <0.05);in0-90days,0-180days than before treatment improved, no significantdifference (P>0.05). The control group with no previous history of hypertension(B2) recovery period phlegm and yin deficiency syndrome score total score at 2weeks,4weeks,90days,180days compared with those before treatment improved,the difference was statistically significant (P <0.05).3Test groups (A) in patients with NIHSS total scores at2weeks,90days,180days compared with those before treatment improved, the difference wasstatistically significant (P <0.05); in4weeks compared with before treatmentimproved, the difference was statistically significant (P <0.05). The testgrouppatients with hypertension (A1) NIHSS total scores at2weeks,4weeks,90days,180days compared with those before treatment improved, the differencewas statistically significant (P <0.05). The test group with no previous historyofhypertension (A2) NIHSS total scores at2weeks compared with before treatmentimproved, no significant difference (P>0.05); in4weeks,90days,180dayscompared with those before treatment improved, the difference wasstatistically significant (P <0.05).4The control group (B) in patients with NIHSS total scores at2weeks,4weeks,90days,180days compared with those before treatment improved, the differencewas statistically significant (P <0.05). The control group patients withhypertension(B1) NIHSS total scores at180days,2weeks compared with beforetreatmentimproved, no significant difference (P>0.05); on the90day,4weekthan before treatment improved, the difference was statistically significant(P <0.05). The control group with no previous history of hypertension (B2)NIHSS total scores at2weeks compared with before treatment improved, nosignificant difference (P>0.05); in4weeks,90days,180days compared withthose before treatmentimproved, the difference was statistically significant(P <0.05).5The test group (A) and control group (B) recovery period phlegm and yindeficiency syndrome total score at week second had better than beforetreatment,the difference was statistically significant (P>0.05); fourth weeks,ninetieth days,180th days compared with those before treatment improved, nosignificant difference (P>0.05); NIHSS total score at2weeks,4weeks,90 days,180dayscompared with those before treatment improved, no significantdifference (P>0.05).6Test groups with no hypertension is high blood pressure recovery phlegmandyin deficiency syndrome total score, total NIHSS score at second weeks, fourthweeks, ninetieth days,180th days compared with those before treatmentimproved,no significant difference (P>0.05).7The control group no previous history of hypertension is high blood pressurerecovery phlegm and yin deficiency syndrome total score, total NIHSS score atsecond weeks, fourth weeks, ninetieth days,180th days compared with those beforetreatment improved, no significant difference (P>0.05).Conclusion：1Integrated traditional Chinese and Western medicine treatment has certaincurative effect on ischemic stroke patients in recovery stage of rehabilitation.2The pure western medicine treatment of ischemic stroke, compared with previoushistory of hypertension patients with no previous history of hypertensionpatientsrecovery recovery, can to some extent shown adverse effects ofhypertension on the recovery of ischemic stroke.3Treatment of ischemic stroke of traditional Chinese medicine and Westernmedicinecombined with3, compared with previous history of hypertension patientswith no previous history of hypertension patients recovery recovery, can reflectthetreatment for hypertension in patients with a history of the restorationof traditional Chinese and Western medicine, there are certain advantages inthe overall effect.