System Evaluation Of TCM Therapy For Hypertension

ObjectivesA randomized controlled trial and a non-randomized controlled trial study of Chinese medicine for the treatment of hypertension were carried out in a comprehensive and systematic manner using evidence-based medicine.The content includeSthe general situation of the present research,the shortcomings,the overall significance of the test results,and some of the randomized controlled studieSfor appropriate meta-analysis,to guide the future treatment of hypertension in Chinese medicine treatment.Methods1.Traditional Chinese medicine combineSsystem evaluation of hypertension The study waSconducted from 1978 to 2016 in the domestic and foreign medical journalSpublished in traditional Chinese medicine treatment of hypertension in a controlled clinical literature,including randomized controlled trialSand non-randomized controlled trials,and then develop evaluation tables,a comprehensive systematic review,The establishment of Excel database,enter the data and double proofreading,the main use of PASW StatisticS18 software for data analysis.2.Traditional Chinese medicine combine Meta analysiSof hypertension The study waSconducted from 1978 to 2016 in the domestic and foreign published articleSon traditional Chinese medicine treatment of primary hypertension in clinical randomized controlled trials.Including journals,compilation of materials,conference papers,academic paperSand other literature.The control group waStreated with traditional Chinese medicine or traditional Chinese medicine and western medicine.The control group waSa randomized controlled trial based on western medicine treatment,and met the curative effect evaluation index.The meta-analysiSof the research data waSmade,,AnalysiSsoftware using Review Manger5.3.Result 1.Appraise systematicallyThrough the Chinese and foreign four major electronic databaseSand manual retrieval,and read the screening,and ultimately into the literature 2167,included in the study of the literature,the research unit of the nature of the main provincial and municipal medical institutions,a total of about 90%,of which the military 7,768 provincial-level units,municipal 531,108 county,24 townships.The main typeSof research unitSmainly in hospitals,a total of about 90%,of which 1376 hospitals,institutionS57,Institute of 11.Research Fund support mainly to fund-based support,accounting for more than 80%,including an international research fund,the national research fund 32,provincial research fund 92,municipal research fund 38,hospital research fund 1,school Level scientific research fund 4 articles.2.Meta analysisMeta analysiSof the object iSfor the treatment of hypertension in Chi nese medicine after the clinical efficacy,systolic blood pressure,diast olic blood pressure,quality of life and other assessment indicators,inc luded a total of 528 randomized controlled study.Meta analysiSshowed that both traditional and traditional Chinese med icine combined with Western medicine in the treatment of traditional Chin ese and Western medicine than the advantage Sof treatment alone.Sensitivi ty analysiSand publication bia SresultSshow that thiSmeta-analysiSthere iS a certain degree of publication bias.ConclusionThe literatureSincluded in the diagnostic criteria,included in the exclusion criteria,efficacy evaluation criteria,most of the literature can refer to the authority of the standard at the time,making the literature of the object,the effect iSmore comparable.However,the overall quality of traditional Chinese medicine in the treatment of hypertension waSpoor,and the lack of multi-center,large sample,double-blind randomized controlled trials.Included in the literature are more stringent randomized controlled clinical efficacy evaluation program design type,but in the specific detailSof the program there is still a lot of room for improvement.Chinese medicine in the treatment of hypertension in the overall efficiency of Western medicine treatment has a certain advantage.Compared with routine treatment with western medicine,pure Chinese medicine therapy and traditional Chinese medicine and western medicine therapy have a certain effect in the treatment of hypertension,but no significant advantages,perhaps with the study of small sample size,observation time is relatively short.Compared with Western medicine,integrated traditional Chinese and Western medicine in the above indicators of efficacy,showing a certain advantage.However,due to the size of the study sample included in this mata-analysis,the severity of the disease may exist correspondingly different,resulting in significant heterogeneity,the results may have some bias on the analysis.Sensitivity analysis results suggest that the impact of OR and SMD values are not large.Results from published biases using funnel plots indicate that the meta-analysis associated with them is stable and the findings of the study are less likely to be published biases.Due to the quality of the clinical randomized controlled study literature included in this analysis,there was a high degree of publication bias in the results of this analysis,expecting more large sample,multi-center,double-blind,placebo-based Chinese medicine Hypertension clinical randomized controlled study carried out and implemented for more higher quality analysis to create favorable conditions,and then guide the treatment of hypertension after Chinese medicine.