ObjectivesThe propose of this experimentation is to observe the therapeutic effects of scrapping therapy based on the theory of midnight-noon ebb-flow on perimenopausal depression, and to compare the therapeutic effects of hormone replacement therapy and midnight-noon and ebb-flow based scrapping therapy, so as to provide some scientific evidence to scrapping therapy based on the theory of midnight-noon ebb-flow on perimenopausal depression.MethodsSeventy-two patients were randomly divided into the treatment group (scrapping therapy based on the theory of midnight-noon ebb-flow group) and the control group (hormone replacement therapy group), with 36 patients in each group. The patients of treatment group should be scrapped on Governor meridian, Bladder meridian, bilateral Shenshu,Ganshu,Pishu,Xinshu,Sanyinjiao,Shenmen,Taixi,Zhaohai and so on, whcih got the treatment two times a week for 8 weeks.Each of the treatment should be given at least at intervals of there days.The patients of control group took the perimarin table once a day for 4 weeks(Medroxyprogesterone Acetate tablet should be given at the beginning of the third week till the end of the fourth week),which formed one course of treatment.The total treament contains two courses.Three scales was used in the research including Improved Kupperman rating scale and Hamilton depression(HAMD) scale,The depression scale on the basis of the symptoms of TCM.AU the data were analyzed with SPSS 18.0 software Package.Results1.The difference of two groups patients was not statistically significan(P>0.05) in age, course of disease,severity of illness, indicating the baseline level of two consistent.2. The recovery rate of treatment group was 41.94%,significantly better than the 16.67% of the control group.The total effective rate was 87.09%, and 76.66% of the control group, and the difference was not statistically significant, indicating that the two groups are both used for treatment of perimenopausal depression.3.After treatment,the treatment group improves well than the control group in the scores of The depression scale on the basis of the symptoms of TCM (P<0.05).4.HAMD of two groups decreased obviously after treatment(P<0.05).After treatment, a month later after that, HAMD scores of the treatment group were obviously lower than the control group (P<0.05).treament group is better at Somatic symptoms and mod changes, while the control group is better at the block of behavior.The treament group is obviously superior to the control group, and after treatment, certain curative effect can be maintained still.5.After treatment, Kuppman scale scores of the treatment group were not obviously different with the control group (P>0.05), suggests that both groups can improve perimenopausal depression in patients with some vasomoLor symptoms; a month later after treatment, The difference of The Kuppman scale scores between two groups was statistically significant (P<0.05), prompting the acupuncture treatment group is still lower with Kuppman scale scores in the end of treatment, especially maintain certain effect.Conclusions1.The scrapping therapy based on the theory of midnight-noon ebb-flow and the hormone replacement therapy can improve the symptoms of the perimenopausal depression patients.2.The scrapping therapy based on the theory of midnight-noon ebb-flow is better on perimenopausal depression.it can not only improve the symptoms of depression,but also the perimenopausal syndrome. |