Assessment Of Cortical Dysfunction In Human Strabismic Amblyopia Using Magnetoecephalography

Objective: Amblyopia is the monocular and binocular developmental disorder which due to the deprivation of form sense and/or the binocular abnormal interaction in the critically period of visual development. The study indicated that the spatial cortical deficit of amblyopia was in V1 and included several brain region. Amblyopia was the combination effects of visual neural pathway.Magnetoencephalography is a completely non-invasive technique which provides a direct assessment of cortial neural activity, the externally recorded magnetic fields reflecting intracellular ionic currents associated with summated post-synaptic potientals. Unlike electrical fields ,magnetic fields are not distored by brain tissue or bone,therefore the measured magnetic fields are directly related to the primary neural source.extensive measurement can be completed on a single subject to obtain high signal-to-noise ratios,thus avoiding the need to average acrosss subjects.Use the technique of magnetoencephaloghay to study the character of the visual evoked field. Discuss the effectes of strabismic amblyopia on the processing of spatial information within the occipital cortex of human and provide a new perspective for the clinical...